摘要
用四甲基氢氧化铵作相转移催化剂,可在常压下由苯胺和溴乙烷合成N,N-二乙基苯胺。研究了多种反应因素对目的产物产率的影响,各影响因素对产率提高的重要性次序依次是:反应物摩尔比>氢氧化钠溶液用量>反应时间>催化剂用量>氢氧化钠溶液质量分数>反应温度。提出了常压下催化合成目的产物的最佳工艺条件是:n(苯胺)∶n(溴乙烷)=1∶2．50,催化剂用量0．40 mL,在45 mL 质量分数为0．50的氢氧化钠溶液中,反应温度65℃,常压反应7 h,产品产率90．6％。
N,N-diethylaniline was synthesized by the reaction of aniline with bromoethane using tetramethy ammonium hydroxide as phase transfer catalyst under atmospheric pressure. The yield of N, N-diethylaniline affected by the various reaction factors has been studied. The results indicate that the influence significance order is mole ratio of aniline to bromoethane 〉 volume of sodium hydroxide solution 〉 reaction period 〉 amount of catalyst 〉 percentage concentration of hydroxide solution 〉 reaction temperature. The optimum parameters were： mole tauo of aniline to bromoethane 1：2.50, amount of catalyst 0.40 mL,the percentage concentration of soldium hydroxide solution 50%, volume of sodium hydroxide solution 45 mL. reaction temperature 65 ℃ , reaction period 7 h under atmospheric pressure. The yield of the target product was 90.6%.
出处
《化工科技》
CAS
2006年第2期1-3,共3页
Science & Technology in Chemical Industry
基金
国家自然科学基金资助项目(60572009)
关键词
N
N-二乙基苯胺
四甲基氢氧化铵
相转移催化
tctramethv ammonium hydroxide
phase transfer catalytic
N, N-diethylaniline
