摘要
目的评价不同水平的C反应蛋白(CRP)分级对易损斑块的鉴别诊断价值。方法对80例住院的冠心病患者分为急性冠状动脉综合征组(43例)和稳定性心绞痛组(37例),分别进行CRP测定和冠状动脉内超声(IVUS)检查,将测得的CRP结果与IVUS结果比较。结果男性CRP水平在急性冠状动脉综合征组明显高于稳定性心绞痛组;女性患者两组间则无显著性差异。以CRP 3.0 mg/L作为分级标准,则对易损斑块诊断的特异性、敏感性和准确性均较高(分别为88.10%,64.42%和81.18%)。结论CRP可作为易损斑块的良好反应指标。
Objective To assess the diagnostic value of serum level of C reactive protein（CRP） for vulnerable plaques. Methods Eighty in-patients were divided into two groups （acute coronary syndrome group, n = 43, and stable angina group, n = 37）. The level of CRP was measured and intravascular ultrasound （IVUS） examination was given to all patients. The results of CRP were compared with that of IVUS. Results In males, the level of CRP in ACS group was higher than that in stable CAD group （ P 〈 0.001 ）, but there was no significant difference in females between the two groups. Using 3.0 mg/L of CRP as the grading standard,the specificity, sensitivity and accuracy were high for diagnosis of vulnerable plaques （88.10%, 64.42% and 81.18 % respectively）. Conclusion Serum level of CRP can be used as a good index reflecting the vulnerable plaques in male patients.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2006年第4期228-230,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
C反应蛋白质
冠状动脉疾病
心绞痛
腔内超声检查
诊断
鉴别
C-reactive protein
coronary disease
angina pectoris
endosonography
diagnosis, differential
