期刊文献+

子痫前期和妊娠期肝内胆汁淤积症孕妇血液脂类变化的分析

下载PDF
导出
摘要 将妊娠32~40周的正常妊娠、子痫前期(PE)、妊娠肝内胆汁淤积症(ICP)分成三组,均为初产妇。年龄23-32岁。对未采用任何治疗者抽取空腹8h的肘静脉血,测定血清游离脂肪酸(FFA)、磷脂(PL)、甘油三酯(TG)、胆固醇(TC)及胆酸(TBA)的水平。结果:TG、TC水平。三组之间无统计学差异,但FFA、PL及TBA水平,均以ICP组为最高(P〈0.05)。结果表明:ICP、PE的发生与甘油三酯、胆固醇升高无关,ICP亦存在着高水平的游离脂肪酸,磷脂的升高具有保护作用。认为FFA和PL可作为子痫前期和ICP的监测指标。
作者 谢滟 杨伟文
出处 《苏州大学学报(医学版)》 CAS 北大核心 2006年第2期319-320,共2页 Suzhou University Journal of Medical Science
  • 相关文献

参考文献12

  • 1乐杰主编..妇产科学 第6版[M].北京:人民卫生出版社,2004:476.
  • 2Jamerson PA.The association between acute fatty liver of pregnancy and fatty acid oxidation disorders[J].J Obstet Gynecol Neonatal Nurs,2005,34(11):87-92. 被引量:1
  • 3章小维,董悦.妊高征与脂代谢[J].中国实用妇科与产科杂志,1998,14(1):14-16. 被引量:5
  • 4Vihma V,Ropponen A,Aittomaki K.Post menopausal estrogen therapy and serum estradiol fatty acid esters in women with and without previous intrahepatic cholestasis of pregnancy[J].Ann Med,2004,36(5):393-399. 被引量:1
  • 5Jacquemin E.Role of multidrug resistance 3 deficiency in pediatric and adult liver disease:one gene for three disease[J].Semin Liver Dis,2001,21(4):551-662. 被引量:1
  • 6Ibdah JA,Yang Z,Benett MJ.Liver disease in pregnancy and fetal fatty acid oxidation defects[J].Mol Genet Metab,2000,71(1-2):182-189. 被引量:1
  • 7Elferink RO.Cholestasis[J].Gut,2003,52 (Suppl 2):42-84. 被引量:1
  • 8Endreson M,Lorentzen B,Heriksen T.Increased lipolyticactivity and high ratio of free fatty acid to albumin in serum from woman with preeclampsia to triglycerides accumulation in cultured endothelial cells[J].Am J Obstet Gynecol,1992,167:440. 被引量:1
  • 9Jamerson PA.The association between acute fatty liver of pregnancy and fatty acid oxidation disorders[J].J Obstst Gynecol Neonatal Nurs,2005,34(11):87-92. 被引量:1
  • 10Bayhan G,Kocyigit Y,Atamer A,et al.Potential atherogenic roles of lipids,lipoprotein(a) and lipid peroxidation in preeclampsia[J].Gynecol Endocrinol,2005,21(1):1-6. 被引量:1

二级参考文献17

  • 1丛克家,王陶陶,刘桂荣,张俊芝.妊高征孕妇的脂质代谢[J].中华妇产科杂志,1994,29(11):651-653. 被引量:35
  • 2郑伟,顾倬云.脂肪乳剂对完全胃肠外营养大鼠血清游离脂肪酸谱的影响[J].营养学报,1995,17(2):193-198. 被引量:5
  • 3张昌颖.生物化学(第2版)[M].北京:人民卫生出版社,1986.118. 被引量:6
  • 4施新猷.医学实验动物学[M].西安:陕西科技出版社,1989.. 被引量:23
  • 5Potter JM,Nestel PJ The hyperlipidemia of pregnancy in normal and complicated pregnancits Am J Obstet Gynecol,1979,133:165 被引量:1
  • 6Van den Blzen Wladimiroff JW,Cohen Overbeek TE,et al Serum lipids in early pregnancy and risk of preeclampsia Br J Obstet Gyncool,1996,103:117 被引量:1
  • 7Satter N,Bendomir A,Berry C,et al Lipoprotein subfraction concentrations in preeclampsia,Pathogenic parallels to atherosclerosis,Obster Gynecol,1997,89:403 被引量:1
  • 8Wang Y, Walsh SW, Guo J, et al. The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood. Am J Obstet Gynecol, 1991 ,165:1695. 被引量:1
  • 9Lim KH, Rice G, Groot CJM, et al. Plasma type Ⅱ phopholipase levels are elevated in severe preeclampsia. Am J Obstet Gynecol, 1995,172 : 998. 被引量:1
  • 10Endreson M, Lorentzen B, Henriksen T. Increased lipolytic activity and high ratio of tree fatly acids to albumin in sera form women with preeclampsia to eriglyceride accumulation in cultured endothelial cells. Am J Obstet Gynecol, 1992,167:440. 被引量:1

共引文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部