摘要
对１５例常规治疗无缓解的重症阻塞性肺病患者进行纤维支气管镜吸痰和灌洗。吸痰和灌洗前、吸痰和灌洗后即刻和吸痰和灌洗后４小时测定肺功能〔时间肺活量第１秒率占预计值的百分比（ＦＥＶ１．０％）〕，吸痰和灌洗时监测血氧饱和度（ＳａＯ２）的变化。结果显示吸痰和灌洗后即刻ＦＥＶ１．０％无显著变化（Ｐ＞０．０５），吸痰和灌洗后４小时ＦＥＶ１．０％由０．４２±０．１２升至０．５７±０．１９，较前显著增高（Ｐ＜０．０１）。吸痰和灌洗时ＳａＯ２稍降低，但吸痰和灌洗后显著增高（Ｐ＜０．０５）。未发现严重的并发症。
15 patients with severe chronic obstructive pulmonary disease (COPD) who could not be relieved by routine therapy were treated by bronchial lavage and aspiration of sputum through bronchoscopy.FEV1 0% was measured before and immeditely after bronchoscopy,and 4h after bronchoscopy.Arterial hemoglobin O 2 saturation (SaO 2) was monitored during bronchoscopy.There was no significant difference in FEV1 0% before and immediately after bronchoscopy( P >0 05).FEV1 0% sgnificantly increased from 0 42±0 12 before bronchoscopy to 0 57±0 19 4h after bronchoscopy.SaO 2 was slightly decreased during bronchoscopy and significantly increased after bronchoscopy( P <0 05).No severe complication was observed.The results showed that bronchial lavage and aspiration of sputum was an effective therapy for severe COPD.
出处
《中国危重病急救医学》
CAS
CSCD
1996年第4期214-215,共2页
Chinese Critical Care Medicine
