摘要
该文报道了12例获得性无巨核细胞性血小板减少性紫癜，该病发病年龄从2月—70岁，女性发病高于男性占66．7％。在本院近四年收治的血小板减少性紫癜中，该病占14％。病人出血症状重，外周血血小板计数为18—85×109／L，骨髓涂片巨核细胞数0—8个／全片．红系、粒系正常。经长春新碱、强的松、达那唑治疗．5例血小板数及巨核细胞数恢复正常。该病可能转化为MDS（骨髓增生异常综合正）、白血病，是否为MDS的另一特正值得进一步探讨。
We investigated 12 Patients with acquired amegakaryocytic purpura (AATP ).The ages of the Patients were from 2 month to 70 years old. The incidence ratio of male to female was 33. 3% to 66. 7%. This group constituted 14% of the hospitalized patients with thrombocytopenic purpura in. the past four years in our hospital. All of the patients had severe bleeding. The platelet number was 18- 85 × 109/L. The megakaryocyte count in marrow smears was 0-8 per slide The megakaryocytes and platelts of five patients returned to normal by using Prednison, VCR and Danazole. It is worth studying that if AATP is one of the pattern of MDS,because AATP may tend to become MDS and leukemia.
出处
《海南医学》
CAS
1996年第1期6-9,共4页
Hainan Medical Journal
关键词
AATP
紫癜
巨核细胞
病理
治疗
Acquired amegakaryocytic thrombocytopenic purpura Megakaryocyte
