摘要
目的 探讨中西医结合治疗血液透析病人慢性低血压的临床效果及作用机制。方法 将63例确诊病人按就诊顺序随机分为治疗组与对照组。对照组给予常规综合治疗如严格限制液量保持液体平衡、设计个体化透析方案、静滴多巴胺等。治疗组在对照组治疗基础上进行中医辩证给予中药煎服，每天1剂，6d为一个疗程，间隔7d，长期服用。随访3年，记录血压变化，血清肾上腺素、去甲肾上腺素水平及肾上腺素a受体，心功能变化抵抗情况并进行比较。结果 治疗组病人的血压改善优于对照组，血清肾上腺素水平虽无统计学意义上的变化（P〉0.05），但肾上腺素受体抵抗及心功能改善优于对照组（P〈0．01）。结论 中西医结合能有效改善血液透析慢性低血压病人的肾上腺素受体功能增强血管反应性，改善心功能。临床疗效显著、持久。
AIM To investigate the effects of Traditional Chinese medicine （TCM） on chronic hypotension in hemodialysis patients.METHODS Hemodialysis patients with chronic hypotension （n=63） received routine comprehensive therapy with Western medicine,33 of whom got TOM besides for consecutive 6 days in 10 - day intervals for years. RESULTS The mean arterial pressure was higher and autoimmune antibody against adrenoreceptor α2 was lower in TCM- treated group. There were no significant differences in serum noradrenaline and adrenaline between TCM - treated and non - TCM - treated patients. CONCLUSION Traditional Chinese medicine has additional effect to Western meditcine on chronic hypotension in hemodialysis patients,
出处
《中华腹部疾病杂志》
2006年第4期250-252,共3页
Chinese Journal of Celiopathy
关键词
中药
血液透析
低血压
中西医结合治疗
Traditional Chinese medicine
Hemodialysis
Chronic hypotension
