摘要
目的探讨丙泊酚复合芬太尼进行人工流产术镇痛的临床效果。方法将400例要求无痛人工流产者随机分为两组,F组(研究组)常规禁食禁饮后静脉注射芬太尼0．05 mg及丙泊酚 1．5 mg／kg;P组(对照组)常规禁食禁饮后静脉注射丙泊酚1．5 mg／kg。术中根据受术者肢体扭动反应追加丙泊酚20-30 mg/次,并记录两组丙泊酚用量、辅用麻黄碱例数、术后宫缩痛例数及清醒时间、离院时间等。结果研究组丙泊酚用量少于对照组,术后宫缩痛例数少于对照组,差异均有统计学意义(P<0．01);研究组辅用麻黄碱例数少于对照组,差异有统计学意义(P<0．05);两组术中 SpO2、清醒时间、离院时间、出现恶心呕吐例数等差异无统计学意义。结论丙泊酚复合芬太尼进行人工流产术镇痛安全有效,临床效果明显优于单独使用丙泊酚。
Objective To compare the effect of propefol and combining propefol with fentanyl for artificial abortion. Methods Four hundreds patients scheduled for painless artificial abortion were randomized to two groups：1. 5 mg/kg of propofol（Group P） or 0.05 mg of fentany and 1.5 mg/kg of propofol（ Group F） were administered respectively. Bolus propofol 20-30 mg was added when the patient moved during the operation. Intraoperative heart rate and blood pressure were monitored. Ephedrine added as needed. Operation time, total consumption of propofol, time of wakening, time of stay in the operation room and postoperative uterine contraction pain were recorded. Results Total comsumption of propofol was less in Group F than that in Group P（ P 〈0.01 ）. Whereas postoperative uterine contraction pain in Group F was lower than that in Group P（ P 〈 0. 01 ）. There were no differences between the two groups in SpO2, time of waking, time of stay in the operation room and the rate of nausia and vomiting. Conclusion Combining fentanyl and propofol can reduce the consumption of anesthetics comparing to propofol alone for patient of painless artificial abortion.
出处
《实用疼痛学杂志》
2006年第2期88-89,共2页
Pain Clinic Journal
