摘要
目的探讨中药方剂过敏煎对婴幼儿湿疹的防治作用。方法57例湿疹患儿随机进入A或B组,A组(治疗组,36例)采用过敏煎加常规治疗,B组(对照组,21例)采用常规治疗。服药前和服药3个月后检测血清IgE、白细胞介素-2(IL-2)、白细胞介素-4(IL-4)。结果A组患儿服药前、后血清IgE的变化与B组比较有统计学差异(P<0.01)。A组患儿服药3个月后复测血清IgE值较服药前有下降。A组患儿服药前、后血清IL-2、IL-4水平变化有统计学差异(P<0.01),服药后IL-2水平升高、IL-4水平降低。最后A组发生哮喘9例(9/36),B组发生哮喘6例(6/21),两组比较P>0.05。A组患儿湿疹发生次数减少、湿疹严重程度减轻。结论过敏煎临床上用于辅佐防治婴幼儿湿疹可达到更好控制症状、减少发作次数、减少皮质激素局部用药的目的。
Objective To evaluate the efficacy and safety of Guominjian to infants with eczema. Methods Fifty-seven infants with eczema were randomly divided into the treated group and the control group, who received treatment of Guominjian and usual treatment respectively. Eczema symptoms and change of serum IgE, IL-2, IL-4 was observed before and after treatment. Results After treatment, significant difference was shown between the two groups, significant improvement was shown in the treated group. Conclusion Guominjian is helpful in improving clinical symptoms, reducing corticosteroids use.
出处
《中国中医药信息杂志》
CAS
CSCD
2006年第4期14-15,共2页
Chinese Journal of Information on Traditional Chinese Medicine
基金
江苏省苏州市科学技术局(SZ02019)
关键词
过敏煎
婴幼儿湿疹
防治
Guominjian
eczema
preventing and treating
