摘要
采用ｐｌｏｔｏｎ银染方法检测１５９例活检胃粘膜的ＡｇＮｏＲｓ，其中胃癌５４例，不典型增生１５例，肠化生１６例，胃溃疡１０例，慢性浅表性胃炎３４例，慢性萎缩性胃炎３０例。结果，各组病变的ＡｇＮｏＲｓ计数为：胃癌１０．９８±１．６９，不典型憎生５．１０±１．５１，肠化生４．４３±１．７６，胃溃疡３．６４±０．８５慢性浅表性胃炎１．６３±０．４６，慢性萎缩性胃炎１．６８±０．５２。经ｔ检验，胃癌组的ＡｇＮｏＲｓ计数显著高于各非癌组，不典型增生和肠化生组的ＡｇＮｏＲｓ计数与其余非癌组间也有显著性差异。认为检测ＡｇＮＯＲｓ方法简单、快速、结果稳定。可作为胃癌和癌前病变诊断的一项辅助指标。
Nucleolar organizer regions associated proteins(AgNORs)in gastric mucosawere studied with argyrophil fechnique in 54 cases of gastric cancer,15 cases of dysplasia,16cases ofintestinal metaplasia,10 caese ofgastric ulcer,34 cases ofchronic superficial gastritis and30 cases of chronic atrophic gastritis.The results were as follows:the mean of AGNORs in eachgroup respectively was:gastric cancer 1098±1,69,dysplasia 5.10±1.51,intestinal metaplasia 4.43±1.76,gastric ulcer 3.64 ± 0.85 chronic superficial gastritis 1.63±0.46 and chronic atrophicgastritis 1.68±0.52.The mean ofAgNORs in gastric cancer was significantly higher than thosefound in all non-cancer groups.Thus,the determination ofthe mean of AgNORs may be used asa parameterin the diagnosis of gastric cancer and pre-cancer states.
出处
《广西医科大学学报》
CAS
1996年第1期44-46,共3页
Journal of Guangxi Medical University
关键词
AGNORS
胃粘膜
活组织检查
AgNORs
gastric cancer
dysplasia
gastric uler
gastritis
