摘要
为探讨神经肽Y(NPY)和神经降压素(NT)两者在原发性高血压(EH)发病中的意义,本文利用RIA法检测了298例EH患者血浆NPY和NT浓度。结果提示,EH患者血浆NPY浓度升高,与病情的严重程度呈正相关;NT浓度下降,与病情的严重程度呈负相关。NPY/NT比例明显升高,与病情相一致。NPY/NT比例失调可能是导致EH发病机制之一。
To study clinical significance of changes and ratio imbalance in neuropeptide Y（NPY） and neurotensin （NT） in patients with essential hypertension（EH）, plasma concentration of NPY and NT in 298 patients with EH was measured by RIA. The results showed that NPY in patients with EH was markedly higher than that in the normal control group, especially in EH cases with stage Ⅲ. The NT values were significantly lower in EH cases as compared with those of the control group. The values of NT in EH patients with stage Ⅲ were lower than those in EH patients stage Ⅰ and/or Ⅱ. The increase of NPY and decrease of NT may be important factors in patients with EH.
出处
《标记免疫分析与临床》
CAS
2006年第1期11-12,共2页
Labeled Immunoassays and Clinical Medicine
