摘要
目的分析肝脏肿瘤超声造影后的组织血流特征与16层螺旋CT三个时期的强化特征,评价其临床诊断价值。方法:研究分析30例病例在超声造影与16层螺旋CT三个时期的各自不同的典型图像。采用经手背静脉注射“全氟显”超声造影剂,利用相干谐波成像技术分析三个时期表现,而16层螺旋CT采用高质量扫描模式,扫描参数:层厚7.5mm,通过拆分成1.25mm,螺距1.375:1,电压120KA,管电流280mA。增强三期扫描分别注射对比剂,动脉期16-25s,门脉期35-55s,延迟期是1min10s-3min。高压注射器单相注射,非离子型造影剂,注射速率2.5ml/s,剂量70-85ml,浓度300mg/ml,通过工作站的技术分析,明确肝肿瘤的强化特点。结果对30例肝脏肿瘤患者进行超声造影与16层螺旋CT检查,其中原发性小肝癌18例,5例小血管瘤,3例局灶性脂肪肝,3例转移性肝癌,1例退变结节。其中有2例超声造影未检测出肿瘤样特征性图像改变,而经CT检测出并诊断为小肝癌1例和退行性结节1例。所有病例均经手术、病理和穿刺证实。结论超声造影与16层螺旋CT对肝脏肿瘤的诊断和鉴别诊断均具有较高的临床应用价值。但对一些特殊肝脏肿瘤患者,联合检测可提高早期诊断的检出率。
Objective To evaluate the value of clinical application of conlrast-enhanced ultrasound and 16 multislice scan in diagnosis of liver neoplasms. Methods The features of three different typical images of three different phases in 30 patients with liver neoplasm detected respectively by contrast-enhanced ultrasound and 16 multislice scan were compared and analyzed. The ultrasound contrast agent, ＂Quanfuxian＂ , was taken by intravenous injection. The different images of three phases were investigated by coherent harmonic imaging. And the high-quality scan mode was adopted by 16 multislice scan. 7.5-mm-thick-section, through division of 1.25mm-section, 1.375：l-pitch, 120KA- voltage and 280mA -tube current were set. The contrast medium was injected for the three enhanced scan phases. The arterial phase was defined as 16-25s, the portal vein phase at 35-55s and the delayed phase at lmin and 10s-3min.The monophase injection of non-ionic conWast agents was utilized by high-pressure syringes. The injection rate, the dosage and the concentration of contrast agent were 2.Sml/s, 70-85ml and 300mg/ml respectively. Results： 18, 5, 3, 3 and 1 out of 30 patients with fiver neoplasms were diagnosed as small hepatocellular carcinoma, small vessels neoplasm, focal hepatic adipose infiltration, metastatic hepatic carcinoma and cataplasia nodus, respectively using contrast-enhanced ultrasound and 16 multislice scan. All cases were confirmed by pathological examinatiom after the operation and puncturatio. Among them, 2 cases were not observed any typical image changes of fiver neoplasms using contrast-enhanced ultrasound, but verified by 16 multislice scan as 1 small hepatocellular carcinoma and 1 cataplasia nodus. Conclusion Both contrast-enhanced ultrasound and 16 multislice scan have high potentiality of clinical application in diagnosis and differential diagnosis of liver neoplasms. But for some unusual patients with liver neoplasms, the combination should improve the early diagnostic ratio.
出处
《CT理论与应用研究（中英文）》
2006年第1期15-20,共6页
Computerized Tomography Theory and Applications
关键词
16层螺旋CT
肝脏肿瘤
超声造影
诊断
16 multislice scan CT
Liver neoplasm
contrast-enhanced ultrasound
diagnosis
