摘要
背景:肠易激综合征(IBS)是临床常见消化系统疾病,业已证实胃肠动力障碍是其病因之一。胃肠起搏是近年兴起的治疗胃肠动力障碍性疾病的新方法,但其疗效尚不明确。目的:评价胃肠起搏治疗IBS的疗效。方法:60例符合罗马Ⅱ标准的IBS患者随机分为2组,治疗组予胃肠起搏治疗,每周5天,每天30min,疗程4周;对照组服用谷维素20mgtid,疗程4周。治疗前后进行胃肠道症状评分。结果:胃肠起搏治疗对IBS患者腹痛和(或)腹部不适程度和频度、腹胀程度和频度以及排便次数和粪便性状的改善具有显著疗效(P<0.05),但对异常排便疗效不明显(P>0.05)。结论:胃肠起搏能明显改善IBS患者的胃肠道症状,是一种较好的治疗方法。
Background： Irritable bowel syndrome （IBS） is a common digestive disease. Gastrointestinal motility disorder is considered as one of its etiological factors. Gastrointestinal pacing is a new method used for the treatment of gastrointestinal motility disorder introduced in recent years, yet its effectiveness has not been well defined. Aims： To evaluate the effect of gastrointestinal pacing on IBS. Methods： In an open clinical trial, 60 patients fulfilling Rome Ⅱ criteria for IBS were randomly allocated into two groups. Treatment group was treated with gastrointestinal pacing （30 min/d, 5 times per week） for 4 weeks, and placebo group took oryzanol 20 mg tid at the same period. The gastrointestinal symptoms score was evaluated before and after treatment. Results： Gastrointestinal pacing could significantly improve the gastrointestinal symptoms of IBS, such as degree and frequency of abdominal pain or discomfort and distension, as well as stool frequency and form （P〈 0.05）. However, abnormal defecation was not remarkable improved from this therapy （P〉0.05）. Conclusions： Gastrointestinal pacing can significantly improve the gastrointestinal symptoms of IBS, it may be the treatment choice for IBS.
出处
《胃肠病学》
2006年第3期172-174,共3页
Chinese Journal of Gastroenterology
关键词
肠易激综合征
胃肠活动
胃肠起搏
治疗结果
Irritable Bowel Syndrome
Gastrointestinal Motility
Gastrointestinal Pacing
Treatment Outcome
