摘要
目的：观察强迫体位所致的骨骼肌损伤过程中线粒体形态的变化。方法：使家兔处于强迫体位不同时间，进行骨骼肌电镜观察和形态计量学分析。结果：强迫体位１周后，线粒体比表面（ＳＳ）与比膜面（ＳＭ）均明显减少；４周后，线粒体ＳＳ明显增加．而ＳＭ仍显著低于对照组；７周后，线粒体ＳＳ与对照组无明显差异，但ＳＭ仍显著低于对照组。结论：强迫体位可造成骨胳肌线粒体的损伤，随强迫体位时间不同．线粒体的形态学变化也不同。
Objective:The aim of this paperis to study the changes of mitochondria of skeletal muscle induced by strained posture,Methods:18 rabbits were divided into experiment and control groups,ex-periment animals were paced in a strained posture for various periods,and Electron Microscopic Mor-phometry was performed on the mitochondria of skeletal muscle of rabbits in strained posture,Results:When the rabbits were in a strained posture for 1 week,the Special Surface (SS)and the Special Membrane(SM)of mitochondria were significantly lower than those of the controls;After 4 weeks,the SS of mitochondria was significantly higher and the SM was significantly lower than those of the con-trols;After 7 weeks,there was not significant difference between experimental and control groups in SS,but the SM of the experimental group was still obviously lower than that of controls. Conclusions:Strained posture can induce mitochondria injury and the morphometry of mitochondria changed with the proloning of experimental time.
出处
《北京医科大学学报》
CSCD
1996年第1期62-64,共3页
Journal of Peking University(Health Sciences)
基金
国家自然科学基金
关键词
形态计量学
线粒体
超微结构
骨骼肌
Headings Morphometry
Mitochondria,Muscle/ultrastruce
Posture
