摘要
目的探讨骨髓检查在不明原因长期发热(FUO)诊断中的临床应用。方法对2001年1月至2005年3月在我院就诊的106例不明原因长期发热患者的骨髓象进行分析。结果在106例不明原因长期发热患者中29例骨髓象有特异性改变,占27.4%。感染性疾病54例(50.9%)其骨髓象多表现为粒系比例上升,粒细胞胞浆内出现中毒颗粒或空泡,中性粒细胞碱性磷酸酶积分升高,其中有17例有骨髓特异性改变。结缔组织病20例(18.9%),其骨髓象多无特异性改变或为溶血性贫血骨髓象表现。肿瘤性疾病14例(13.2%),其中12例骨髓象可发现白血病或肿瘤细胞。在10例(9.4%)其它疾病和8例(7.5%)仍未诊断明确的疾病中无特异性表现。结论骨髓形态学改变在长期发热患者的诊断中起着重要作用,对于不明原因长期发热患者应及时做骨髓检查。
Objective To investigate the value of bone marrow examination in the fever of unknown origin （FUO）. Methods The bone marrows of 106 cases with fever of unknown origin were reviewed between January 2003 and March 2005.Results 29 cases of 106 had specific bone marrow feature. Infectious diseases were responsible for 50.9% （54/106） of FUO,in which cases neutrophils ratio rose, toxic granulation or vacuoles appeared in neutrophils, neutrophils alkaline phosphatase was higher than normal, 17 cases had specific bone marrow feature among them. Conneetive tissue diseases were responsible for 18.9 % （20/106） of FUO, these cases had unspecific or hemolytic anemia bone marrow feature. Neoplasm were responsible for 13.2% （14/106） of FUO, Leukemia or tumor cells could be found in these cases. 10（9.4% ）the other diseases and 8（7.5%） the cases without explicit diagnosis had not specific bone marrow feature.Conclusion Bone marrow morphology can provide useful information in diagnosis of FUO. Patients with FUO should do bone marrow examination in time.
出处
《中国实验诊断学》
2006年第3期278-279,共2页
Chinese Journal of Laboratory Diagnosis
关键词
不明原因的发热
骨髓检查
fever of unknown origin
bone marrow examination
