期刊文献+

Survivin与癌基因相互作用对儿童白血病细胞凋亡的影响 被引量:3

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摘要 Survivin是一种新近发现的凋亡抑制蛋白,通过抑制Caspase-3、7活性而抑制细胞凋亡,还参与细胞周期调控。Sur-vivin选择性的在肿瘤组织表达而在正常成熟组织不表达,其与肿瘤发生、发展有关,并可能是导致肿瘤细胞耐药的因素,是肿瘤靶向治疗的一个很好的靶基因。
作者 侯燕 胡群
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2006年第5期310-312,共3页 Journal of Applied Clinical Pediatrics
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参考文献13

  • 1孟小莉.急性非淋巴细胞白血病细胞survivin mRNA的表达[J].郑州大学学报(医学版),2004,39(6):1035-1036. 被引量:2
  • 2Ambrosini G,Adida C,Altieri DC.A novel anti-apoptosis gene,survivin,expressed in cancer and lymphoma[J].Natl Med,1997,3:917-921. 被引量:1
  • 3Suzuki A,Hayashida M,Ito T,et al.Survivin initiates cell cycleentry by the competitive interaction with CDK4/P16INK4a and CDK2/cyclin E complex activation[J].Oncogene,2000,19:3225 -3234. 被引量:1
  • 4Aggarwal BB,Ichikawa H.Molecular targets and anticancer potential of indole-3-carbinol and its derivatives[J].Cell Cycle,2005,4(9):1201-1215. 被引量:1
  • 5Blanc-Brude OP,Mesri M,Wall NR,et al.Therapeutic targeting of the survivin pathway in cancer:initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis[J].Clin Cancer Res,2003,9(7):2683-2692. 被引量:1
  • 6Lacasse EC,Baird S,Korneluk RG,et al.The inhibitors of apoptosis (IAPs) and their emerging role in cancer[J].Oncogene,1998,17:3247-3259. 被引量:1
  • 7Gunawardena K,Campbell LD,Meikle AW.Antiandrogen-like actions of an antioxidant on survivin,Bcl-2 and PSA in human prostate cancer cells[J].Cancer Detect Prev,2005,29(4):389-395. 被引量:1
  • 8Hoffman WH,Biade S,Zilfou JT,et al.Transcriptional repression of the anti-apoptotic survivin gene by wild type p53[J].J Biol Chem,2002,277 (5):3247-3257. 被引量:1
  • 9Mirza A,McGuirk M,Hockenberry TN,et al.Human survivin is negatively regulayted by wild-type p53 and participates in p53 -dependent apoptotic pathway[J].Oncogene,2002,21:2613-2622. 被引量:1
  • 10Das A,Tan WL,Teo J,et al.Expression of survivin in primary glioblastomas[J].J Cancer Res Clin Oncol,2002,128:302-306. 被引量:1

二级参考文献23

  • 1Sarela AI, Macadam RC, Farmery SM, et al. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma [J]. Gut, 2000, 46(5) : 645-650. 被引量:1
  • 2Ambrosini G, Adida C, Altieri DC. A novel anfi-apoptosis gene,survivin, expressed in cancer and lymphoma [J]. Nat Med,1997, 3 (8): 917-921. 被引量:1
  • 3Kawasaki H, Altieri DC, Lu CD, et al. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer[J]. Cancer Res, 1998, 58 (22): 5071-5074. 被引量:1
  • 4Suzuki A, ho T, Kawano H, et al. Survivin initiates procaspase3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death [J]. Oncogene, 2000, 19. 被引量:1
  • 5Li F, Ambrosini G, Chu EY, et al. Control of apoptosis and mitotic spindle checkpoint by survivin[J]. Nature, 1998, 396(6711): 580-584. 被引量:1
  • 6Maehama T, Dixon JE. The tumor suppressor, PTEN/MMACI,dephosphorylates the lipid second messenger,phosphatidylinositol 3, 4, 5-trisphosphate [J]. J Biol Chem,1998, 273(22): 13375-13378. 被引量:1
  • 7Myers MP, Stolarov JP, Eng C, et al. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificityphosphatase [J]. Proc Nail Acad Sci USA, 1997, 94 (17) :9052-9057. 被引量:1
  • 8Carter BZ, Milella M, Ahieri DC, et al. Cytokine-regulated expression of survivin in myeloid leukemia [J]. Blood, 2001, 97(9): 2784-2790. 被引量:1
  • 9Suzuki A, Hayashida M, lto T, et al. Survivin initiates cell cycle entry by the competitive interaction with Cdk4Jpl6(INK4a) and Cdk2/CyclinE complex activation [J]. Oncogene, 2000, 19(29):3225-3234. 被引量:1
  • 10Tamm I, Wang Y, Sausville ED, et al. IAP - family protein Survivin inhibits Caspase activity and apoptosis induced by Fas(CD59),Bax,Caspase,and anticancer drugs[J]. Cancer Res, 1998,58(23):5315 - 5320. 被引量:1

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