摘要
背景:认识血压的不同成分对脑血管病的影响及在疾病不同情况下正确使用降压治疗均具有重要意义。目的:通过对急性脑梗死患者的入院脉压分析,探讨脉压增大与脑梗死的发生、严重程度的相关性。设计:病例-对照分析。单位:哈尔滨医科大学附属第一医院。对象:病例组为2002-06/2003-01因缺血性脑梗死入住哈尔滨医科大学附属第一医院的患者300例,男196例,女104例鸦年龄(57.9±11.9)岁。正常组为在同期来本院进行体检者199例,男110例,女89例鸦年龄(55.9±12.4)岁。方法:①血压测量:安静状态下应用水银柱血压计按标准方法选择右上肢肱动脉处测血压。记录患者的收缩压和舒张压,并计算脉压。②神经功能缺损评分:应用美国国立卫生研究院卒中量表在入院时对每例缺血性脑梗死患者进行临床神经功能缺损评分,以入院时评分作为脑卒中严重程度的评价指标,分值越大,脑卒中程度越重。主要观察指标:①两组对象血压各参数比较。②两组对象中不同脉压水平人员分布情况。③两组中不同年龄段人群脉压比较。④不同脉压水平脑梗死患者神经功能缺失评分非参数检验结果。结果:①平均收缩压:病例组明显高于对照组眼(152±22),(133±19)mmHg,t’=10.494,P<0.01演。平均舒张压:病例组明显高于对照组眼(93±14),(81±11)mmHg,t’=10.129,P<0.01演。平均脉压:病例组脉压高于对照组眼(59.61±11.86),(51.93±14.10)mmHg,t’=5.612,P<0.05演。两两相关分析结果显示,脉压与收缩压的Pearson相关系数为0.789(P<0.01),脉压与舒张压的Pearson相关系数为0.169(P<0.01),故可以认为脉压与收缩压的相关性更密切。②在病例组,脉压最大的分布区域在60～69mmHg,占27.7%;对照组脉压最大的分布区域在40～49mmHg,占35.7%。提示脑梗死时脉压大于60mmHg的发生率较高。③随着年龄的增加,脉压增大。40～69岁病例组的脉压水平明显高于
BACKGROUND： It is of great significance to understand the effects of different components of blood pressure on the occurrence of eerebrovascular diseases and administer proper decompression treatments in various situations. OBJECTIVE： To study the relationship of increased pulse pressure with the occurrence and severity degree of cerebral infarction by analyzing the data of pulse pressure recorded in hospitalized patients with acute cerebral infarction. DESIGN： Case-control analysis. SETTING： First Affiliated Hospital of Harbin Medical University. PARTICIPANTS： A total of 300 patients hospitalized at the First Affiliated Hospital of Harbin Medical University between June 2002 and January 2003 for ischemic cerebral infarction were enrolled, including 196 males and 104 females aged （57.9±11.9） years. Another 199 persons who came to the same hospital for physical examination at the same period were set as normal group, including 110 males and 89 females aged （55.9±12.4） year8. METHODS： ① Measurement of blood pressure： Systolic pressure and diastolic pressure of each person were recorded with mercury sphygmomanometer at the site of brachial artery of the right upper extremity and pulse pressure was calculated. ② Evaluation of neurological impairment： Upon hospital admission, each patient with ischemic cerebral infarction was evaluated with the stroke scale made by the National Institute of Health （NIHSS）, in which a higher score means more severe infarction. MAIN OUTCOME MEASURES： ① Comparison of blood pressure parameters of subjects in the two groups. ② Distribution of different pulse pressure levels in the two groups. ③ Comparison of pulse pressure of subjects of different age in the two groups. ④ Results of non-parameters tests of neural function loss in cerebral infarction patients with different pulse pressure levels. RESULTS： ① Mean systolic pressure： It was significantly higher in the case group than in control group [（152±22）, （133±19） mm Hg, t＇ =1
出处
《中国临床康复》
CSCD
北大核心
2006年第12期167-169,共3页
Chinese Journal of Clinical Rehabilitation
