摘要
目的通过用自行设计的口内测量器械对阻塞性睡眠呼吸暂停低通气综合症(OSAHS)患者进行悬雍垂腭咽成形术(UPPP)术前口内参数测量,以确定阻塞部位及手术切除范围,术后口内测量用以评价手术疗效。通过观察OS-AHS患者UPPP术前、术后的红细胞计数(RBC)、血红蛋白浓度(HGB)、红细胞压积(HCT)等相关指标,研究RBC、HGB、HCT是否可以作为筛选OSAHS患者的指标。方法研究对象为2003年3月至2005年3月在中国医科大学附属第一医院耳鼻咽喉科接受手术的患者。在术前及术后1个月,对每名受试对象进行口内相关参数测量:包括软腭长、悬雍垂长、咽侧距、软腭与咽后壁距。并对这些数据进行统计学分析。记录每名受试对象术前、术后1个月的RBC、HGB、HCT等相关参数,进行统计学分析。结果对照组与OSAHS患者组术前口内测量软腭长、悬雍垂长比较无统计学意义,而咽侧距、软腭与咽后壁距有显著性差异。OSAHS患者术前、术后1个月咽侧距、软腭长、悬雍垂长、软腭与咽后壁距口内测量结果比较有统计学意义(P<0.01)。40例OSAHS患者术前、术后1个月血常规中RBC、HGB、HCT等相关指标比较差别有统计学意义(P<0.01)。结论应用自行设计的口内测量器械可以对OSAHS患者术前进行阻塞定位。RBC、HGB、HCT可以作为衡量OSAHS患者术前病情严重程度及术后恢复情况的指标。用自行设计的口内测量器械结合Epworth嗜睡量表及术前血常规中RBC、HGB、HCT等指标可以作为筛选OSAHS患者的一种方法。
Objective To collect the obstructive sleep apnea-hypopnea syndrome patients＇ data in pre＆post-operation using the self-designed intra-oral measure appliances, to define obstructive position and resected range and evaluate the efficiency of operation. Before and after U-vulopalatopharyngoplasty, observed Red blood cell, Hemoglobin and Hematocrit in OSAHS patients, and studied whether they could be used to evaluate the state of OSAHS. Methods The measurements of each patient included： length of softpalate, distance of pharynx, distance of palatopharynx and length of uvula in pre ＆ post-operation a month. These data were analyzed statistically. Recorded and analyzed these experiment data by means of statistical software of EXCEL. A set of self-designed intra-oral measure appliances. Results Palatopharykgeal data of normal and OSAHS group were as followed： distance of pharynx and distance of palatopharynx were significantly different except for length of softpalate and length of uvula （independent t-test, P〈0.01 ）. The data of OSAHS group was significantly different in pre ＆ post-operation （paired-sample t-test P〈O.01 ）. Red blood cell （RBC）, Hemoglobin （HGB）, and Hematocrit （HCT） were significantly different in OSAHS group （40cases） in pre ＆ post-operation a month （paired-sample t-test P〈0.01 ）. Conclusion Using self-designed intra-oral measurement appliance to define the position of obstruction and accurate resected range in OSAHS patient, furthermore each patient can gain high efficiency of operation than before. RBC ,HGB, HCT can be regarded as the indexes of evaluating patients＇ condition in OSAHS, and recovering state post-operation. OSAHS patients＇ illness situation can be evaluated by means of using self-designed intra-oral measure appliances, accompany with Epworth sleepness scate, and RBC ,ttGB,HCT of pre-operation.
出处
《中国现代医药杂志》
2006年第1期4-7,共4页
Modern Medicine Journal of China
