摘要
目的:研究大鼠应激性溃疡自愈过程中胃肠激素的变化。方法:应用束缚浸水应激(W ater-imm ers ion andrestra in t stress,W RS)方法制作大鼠应激性溃疡(S tress u lcer,SU)模型。应用放射免疫分析法检测大鼠SU自愈过程中胃肠激素的动态变化。结果:大鼠SU自愈过程中胃泌素、前列腺素E2、表皮生长因子明显增加,生长抑素明显减少。结论:大鼠SU自愈过程中胃泌素、前列腺素E2、表皮生长因子明显增加,生长抑素明显减少。胃泌素、前列腺素E2、表皮生长因子对SU的自愈有促进作用。
Objective：To investigate the changes of gut hormone during the autotherapy from the stress ulcer in rats. Methods：The model of stress ulceration was established by WRS. Radioimmunoassay was performed to measure the changes of gut hormone during autotherapy. Result ;Contents of gastrin, prostaglandin E and EGF were increased significantly and content of somatostatin declined significantly during recovery from stress ulceration. Conclusion： Gastrin, prostaglandin E and EGF could promote the autotherapy from stress ulceration in rats.
出处
《中国误诊学杂志》
CAS
2006年第4期604-606,共3页
Chinese Journal of Misdiagnostics
关键词
胃溃疡/代谢
胃肠激素类/代谢
Stomach ulcer/metabolism
Gastrointestinal hormones/metabolism
