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急性白血病患者血浆VEGF、TF和IL-6的测定及其临床意义 被引量:4

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摘要 目的:探讨急性白血病(AL)患者血浆血管内皮细胞生长因子(VEGF)、组织因子(TF)和白细胞介素-6(IL-6)含量变化与临床病情的关系。方法:用双抗体夹心酶联免疫吸附法(ELISA)检测32例AL患者血浆VEGF、TF和IL-6含量。结果:AL初治患者血浆VEGF、TF和IL-6含量明显高于对照组,也明显高于缓解组(P<0.005或0.001),未缓解组患者血浆VEGF、TF和IL-6含量与初治组比较差异无显著性(P>0.05);且AL患者血浆IL-6与VEGF、TF增加呈正相关(r=0.45、0.41,P<0.05)。结论:AL患者血浆TF、VEGF和IL-6含量与临床病情变化密切相关,可作为了解病情、观察疗效、判断预后的指标之一。
出处 《实用医学杂志》 CAS 2006年第5期541-542,共2页 The Journal of Practical Medicine
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