摘要
目的探讨男性2型糖尿病患者血清总睾酮(T)、总雌二醇(E2)及性激素结合蛋白(SHBG)的变化。方法选取正常男性37例,2型糖尿病男性患者46例,采用酶联放射免疫法测定血清胰岛素、总T、总E2、SH-BG含量。结果男性2型糖尿病患者较正常对照组总T降低,总E2、SHBG升高。男性2型糖尿病患者总T、总E2、SHBG与空腹胰岛素、120分胰岛素之间无明显相关性。结论血清性激素是反映男性2型糖尿病患者代谢变化的较好指标之一。
Objective To investigate the levels of serum testosterone, estradiol and sex hormonebinding globulin in male patients type 2 diabetes mellitus. Methods 46 male patients with type 2 diabetes mellitus, and 37 normal males were investigated. Serum levels of testosterone （T）, estradiol （Fa）, sex hormone-binging globulin （SHBG） and insulin were determined at the same time by ELISA. Resuits Compared with controls, the level of serum testosterone were decreased, and serum estradiol ad sex hormone-binding globulin levels were increased in type 2 diabetic male. It was also showed that no significant relationship between insulin and T, E2 or SHBG was found in male patients with type 2 diabetes mellitus. Conclusion The serum levels of T, E2 and SHBG are the perfect index showing the metabolic changes in male paltieuts with type 2 diabetes mellitus.
出处
《咸宁学院学报（医学版）》
2006年第1期26-27,共2页
Journal of Xianning Univarsity(medical Sciences)
关键词
2型糖尿病
睾酮
雌二醇
性激素结合蛋白
Type 2 diabetes mellitus
Testosterone
Estradiol
Sex hormone-binging globulin
