摘要
目的了解老年人群中体重指数(BMI)与代谢综合征患病及相关代谢异常之间的关系。方法683例65岁以上(平均71·2岁)的老年男性,以中华医学会糖尿病学分会制订的代谢综合征工作定义作为标准,按照BMI进行分层,分析不同BMI人群代谢综合征的患病率及各项代谢指标的异常情况。结果(1)当BMI≥23kg/m2时,代谢综合征的患病率随BMI的增加显著上升,BMI和代谢异常数量之间呈现一种正相关趋势(r=0·557);(2)BMI增加与收缩压(SBP)、舒张压(DBP)、血甘油三酯之间正相关(r值分别为0·189、0·198和0·201),与血高密度脂蛋白胆固醇之间负相关(r=-0·157);(3)在血压正常人群和在非糖尿病人群,BMI与SBP、DBP、空腹血糖及餐后2h血糖之间显著正相关;(4)冠心病和肾脏损害患者的BMI显著高于无相关疾病人群(P<0·05);(5)冠心病、肾脏损害和脑血管病变患者中的代谢综合征患病率显著高于没有这些疾病的人群(P<0·05)。结论随着BMI的增加,代谢指标异常的数量逐渐增加,代谢综合征的患病率也逐渐升高。BMI的增加与冠心病、肾脏损害和脑血管病变的发病相关。
Objective The aim of the study is to determine the relationship between body mass index （BMI） and metabolic syndrome and to investigate the epidemiological characteristics of this syndrome in elderly men. Methods A survey was conducted among 683 elderly men aged 65 years and over. To identify the prevalence of metabolic syndrome and epidemiological condition of some metabolic indexes after grading with BMI, the working definition of Chinese Diabetes Society was accepted. The relationship between BMI and certain diseases was analyzed. Results （ 1 ） The prevalence of metabolic syndrome increased concomitantly with the increase of BMI, when BMI was beyond 23 kg/m^2. （2）There was positive correlation between BMI and the number of the abnormal metabolic indexes （ r = 0. 557 ）. （ 3 ） There was positive correlation between the increase of BMI and the levels of systolic blood pressure （SBP） , diastolic blood pressure （DBP） and triglyceride level （ r = 0. 189,0. 198 and 0. 201 respectively）. There was negative correlation between the increase of BMI and the level of high density lipoprotein cholesterol （ r = - 0. 157）. （4） There was positive correlation between the increase of BMI and the levels of SBP （r =0. 140） and DBP （r = 0. 202） in non-hypertensive population. （5） There was positive correlation between the increase of BMI and the levels of fasting blood glucose （r =0. 103 ） and postprandial blood glucose （r = 0. 113 ） in nondiabetic population. （6）There was significant increase of BMI in the population with coronary heart disease and impairment of kidney function （P 〈0. 05）. （7）The prevalence of metabolic syndrome was significantly elevated in the population with coronary heart disease, impairment of kidney function and cerebrovascular disease （P 〈0. 05）. Conclusions When BMI is increased, the number of abnormal metabolic indexes is increased and the prevalence of metabolic syndrome is elevated as well. In the population with the above m
出处
《中华内科杂志》
CAS
CSCD
北大核心
2006年第2期100-103,共4页
Chinese Journal of Internal Medicine
关键词
体重指数
肥胖症
代谢综合征
Body mass index
Obesity
Metabolic syndrome
