摘要
对遵义地区居民中应用开放式炉灶的、经保守治疗无效的萎缩性鼻炎(AR)患者行鼻域缩窄术,于术前术后钳取鼻粘膜行病理和组织化学观察,并以正常人作为对照。结果是:手术前与手术后3个月比较差异不明显;但随时间的延长鼻粘膜均有显著的变化。术后6年鼻粘膜几乎恢复达正常程度,但恢复的假复层柱状上皮仍有部分纤毛脱落;固有层中腺体数量增加,但腺体部分细胞排列不整;血管内膜虽未见明显增厚,但血管周围仍有炎细胞浸润(对照组则无)。故术后仍未能恢复到完全正常程度,结合本地区AR特点,提示应加强AR的预防工作;鼻阈缩窄手术仍不失为治疗AR的一种好方法。
The atrophic rhinitis's(AR) patients who used opentype store and were not cured by conservative treatment were divided into operative group and nonoperative group,with the normal persons as controls. Histopathological and histochemical studies were performed in order to seek the pathogenesis and the direction of prevention and cure. The results showed that the changes of preoperation and that of postoperation were significantly different in company with the extension of the duration of the time. The AR patients nearly recovered in six years after operation. But the recovered pseudo columnar cilliated epithelium still showed a partial shedding of cillis. The number of glands was increased in tunica propria. However,some cells of glands were arranged in bad order. Inflammatory cells revolved round the blood vessels (But they didn't occur in the controls). Although the endangium was not significantly thickened. For this reason,the patients did not fully recover from AR. On the basis of charactristics of AR in Zunyi the prephylaxis should be strengthened. However,the surgery may after all be accepted as a better way of AR therapy.
出处
《临床耳鼻咽喉科杂志》
CSCD
1996年第1期12-14,共3页
Journal of Clinical Otorhinolaryngology