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复合酶在生物合成中的应用

Utilization of Enzyme Mixtures for Complex Biosyntheses
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摘要 目前生物催化主要用于更加经济简便的合成已知和未知的化合物。利用突变的微生物、加工酶及新颖的酶的复合,可以提高产量,也可以探索出新式合成方法。复合酶的应用利用了系统水平的生物学知识,成为新式的化合物合成方法。随着对蛋白质功能及其相互作用的逐步了解,这种体外的生物合成方法也正在进一步得到完善。 Biocatalysis is currently employed to produce known substances more economically and for the synthesis of new compounds. Increased production or novel product synthesis can be achieved through the use of mutant organisms, tailored enzymes or novel combinations of enzymes in reactors. These complex biosyntheses, once only used in the realm of the biopharmaceutical industry, have now been embraced by the food and textile industries and are finding new geochemical and environmental applications. The use of enzyme mixtures is becoming a novel manufacturing methods that utilize the systematic biological knowledge. The enhanced understanding on the functional interaction of proteins and protein networks is also altering the practice of in vitro biosynthesis.
出处 《食品与生物技术学报》 CAS CSCD 北大核心 2006年第1期115-119,共5页 Journal of Food Science and Biotechnology
基金 国家自然科学基金项目(20176019)
关键词 复合酶 生物合成 组合 enzyme mixt ures biosynthesis combination
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