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CFL2基因研究进展 被引量：6

Advances in the Research of CFL2 Gene
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摘要 CFL2(Cofilin2)基因是肌动蛋白结合蛋白cofilin家族的新成员,主要在哺乳动物的骨骼肌和心肌表达,被认为是肌肉组织肌动蛋白装配的调节器,对正常肌肉功能和肌肉再生起着重要的作用。目前未见对CFL2基因进行全面介绍的文章,因此拟对CFL2基因的表达、结构、蛋白功能及其与肌病相关性方面的研究进展作一综述。 CFL2 （Cofilin 2）is a new member of the cofilin family of actin-binding proteins, which is expressed predominantly in mammals skeletal muscle and heart. CFL2 is a regulator for actin assembly in muscle and may plays an important role in normal muscle function and muscle regeneration. The overall articles on the CFL2 gene are not been reported currently. T his text makes an overview about the expression and the structure of CFL2gene, protein functions and its role in myopathies.
作者 宋慧娟 苏玉虹
机构地区 锦州医学院辽宁省高校分子细胞生物学与新药开发重点实验室
出处 《中国农学通报》 CSCD 2006年第2期28-30,共3页 Chinese Agricultural Science Bulletin
基金 辽宁省科技厅博士启动基金(20021072) 辽宁省教育厅基金(2004F112)资助项目。
关键词 CFL2基因 肌动蛋白结合蛋白 肌病 CFL2, Actin-binding protein, Myopathy
分类号 Q71 [生物学—分子生物学]
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参考文献24

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二级参考文献8

共引文献25

同被引文献63

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引证文献6

二级引证文献25

中国农学通报
2006年 第2期

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