期刊文献+

原发性醛固酮增多症患者心血管和肾功能指标的改变 被引量:11

下载PDF
导出
摘要 目的研究原发性醛固酮增多症(简称原醛)患者心血管和肾功能指标的改变情况,探讨醛固酮水平对心脏和肾脏的病理作用。方法收集178例原醛患者的病史资料,研究患者心血管指标和肾功能的改变情况及其临床表现,分析血尿醛固酮水平、高血压等因素与心肌肥厚、尿微量白蛋白和肌酐的关系。结果本组患者中,32.0%有心肌肥厚,40.1%尿微量白蛋白异常,9.2%肌酐超过正常上限。心肌肥厚与非肥厚患者的醛固酮水平无明显差别。微量白蛋白尿异常和肌酐升高均与高血压和醛固酮水平呈相关性(P<0.05)。结论原醛患者有较高的心脏和肾脏病变率,醛固酮增多和高血压是其主要致病原因。
出处 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2006年第1期48-50,共3页 Journal of Shanghai Jiao tong University:Medical Science
  • 相关文献

参考文献12

  • 1[1]Struthers DA.Aldosterone:an important mediator of cardiac remodeling in heart failure[J].Br J Cardiol,2005,12(3):211-218. 被引量:1
  • 2[2]Ganguly A.Primary aldosteronism[J].N Engl J Med.1998; 339(25):1828-1834. 被引量:1
  • 3张炜,汤正义,吴景程,赵咏桔,宁光.正常血压的腺瘤型原发性醛固酮增多症一例[J].中华医学杂志,2005,85(15):1073-1073. 被引量:8
  • 4[4]Rossi GP,Sacchetto A,Pavan E,et al.Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma[J].Circulation,1997,95(6):1471-1478. 被引量:1
  • 5[5]Williams JS,Williams GH.50th anniversary of aldosterone[J].J Clin Endocrinol Metab,2003 88(6):2364-2372. 被引量:1
  • 6吕朝晖,郑蕾,田慧,陆菊明.原发性醛固酮增多症高血压临床特点的研究[J].解放军医学杂志,2003,28(5):419-421. 被引量:13
  • 7[7]Tekeda R,Matsubara T,Miyamori I,et al.Vascular complications in patients with aldosterone producing adenoma in Japan:comparative study with essential hypertension.The Research Committee of Disorders of Adrenal Hormones in Japan[J].J Endocrinol Invest,1995,18(5):370-373. 被引量:1
  • 8[8]Conn JW,Knopf RF,Nesbit RM,et al.Clinical characteristics of primary aldosteronism from an analysis of 145 cases.Am J Surg,1964,107:159-168. 被引量:1
  • 9[9]Karalliedde J,Viberti G.Microalbuminuria and cardiovascular risk[J].Am J Hypertens,2004; 17(10):986-993. 被引量:1
  • 10[10]Gosse P.Left ventricular hypertrophy as a predictor of cardiovascular risk[J].Left ventricular hypertrophy as a predictor of cadiovascular risk.J Hypertens Suppl,2005,23(1):S27-S33. 被引量:1

二级参考文献11

  • 1[4]Vantyghem MC, Ronci N, Provost F et al. Aldosterone-producing ade noma without hypertension: a report of two cases. Eur J Endocrinol, 1999, 141:279 被引量:1
  • 2[5]Conn JW, Knopf RF, Nesbit RM. Clinical characteristics of primary al dosteronism from an analysis of 145 cases. Am J Surg, 1964, 107:159 被引量:1
  • 3[6]Sumitomo H, Yamashita N, Katayama S. A case report of aldosterone producing adrenocortical adenoma complicated with chronic renal failure associated with nephrocalcinosis: review of APAs complicated with chro nic renal failure. Folia Endocrinol, 1995, 71:115 被引量:1
  • 4[7]Greene EL, Kren S, Hostetter TH. Role of aldosterone in the remnant kidney model in the rat. J Clin Invest, 1996, 98:1063 被引量:1
  • 5[8]Ibrahim HN, Hostetter TH. The renin-aldosterone axis in two models of reduced renal mass in the rat. J Am Soc Nephrol, 1998, 9:72 被引量:1
  • 6[9]Beevers DG, Brown J J, Ferriss JB et al. Renal abnomalities and vascular complications in primary hyperaldosteronism. Evidence on tertiary hyper aldosteronism. QJ Med, 1976, 45:401 被引量:1
  • 7[10]Rocha R, Chander PN, Khanna K et al. Mineralocorticoid blockade re duces vascular injury in stroke-prone hypertensive rats. Hypertension, 1998, 31:451 被引量:1
  • 8[1]Young SC, Shionoiri H, Takasaki I etal. Hypertensive complications in patients with primary aldosteronism. A retrospective study. Curt TherRes,1991, 50:317 被引量:1
  • 9[2]Takeda R, Matsubara T, Miyamori I et al. Vascular complications in pa tients with aldosterone-producing adenoma in Japan: comparative study with essential hypertension. The Research Committee of Disorder of Ad renal Hormones in Japan. J Endocrinol Invest, 1995, 18:370 被引量:1
  • 10[3]Nishimura M, Uzu T, Fujii T et al. Cardiovascular complications in pa tients with primary aldosteronism. Am J Kidney Dis, 1999, 33:261 被引量:1

共引文献19

同被引文献149

引证文献11

二级引证文献58

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部