摘要
目的:观察中药胃康胶丸对大鼠急性胃损伤后黏膜血流的影响。方法:采用寒冷应激法诱发急性胃损伤大鼠模型,给药7 d后,用激光多普勒血流仪测定胃黏膜血流。结果:胃康胶丸组大鼠胃黏膜血流明显高于模型组,胃组织损伤评分均明显低于模型组。与其他给药(L-谷氨酰胺、枸橼酸铋钾、金银花)组比较,胃康胶丸组的作用更明显(P<0．01)。结论:胃康胶丸可以增加胃黏膜血流量,促进修复。
Objective：To assess the effect of Weikang capsules on acute gastric mucosa lesions of rats. Methods：Following after the induction of acute rat gastric mucosa lesions by cold stress, the rats were treated with Weikang capsules for 7 days. The gastric mucosal blood circulation was measured by a laser doppler blood flow instrument. Results： The Weikang capsules significantly reduced the gastric mucosa lesion index, and increased the gastric mucosal blood circulation of rats, compared with the lesions model group （P〈0.01 ）. The protection effect of Weikang capsule was superior to that of other groups treated with glutamine granula, bismuth potassium citrate and Flos Lonicerae,respectively. Conclusion： Weikang capsules could recover acute rat gastric mucosa lesion better.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2006年第1期33-35,i0001,共4页
Chinese Journal of New Drugs
基金
国家自然科学基金资助项目（30472100/C030404）
关键词
胃康胶丸
胃损伤
胃黏膜血流
大鼠
Weikang capsule
gastric mucosal damage
gastric mucosal blood flow
rats
