摘要
目的评价子宫动脉平阳霉素碘油乳剂栓塞对子宫腺肌病患者卵巢功能的影响。方法对33例子宫腺肌病患者用平阳霉素碘油乳剂进行子宫动脉栓塞,并检测栓塞前和栓塞后第1、3、6和12个月的患者以及45例正常体检女性(对照组)同期血中的雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)和催乳素(PRL)水平,其后对两组结果作比较研究。结果栓塞前33例患者的FSH、LH、E2水平与正常对照组差异无显著性(P>0.05),而PRL水平高于正常对照组(P<0.05);栓塞术后1、3、6和12个月的患者FSH、LH、E2皆与术前无显著性差异(P>0.05),但PRL水平较栓塞前明显下降(P<0.05)。结论子宫动脉平阳霉素碘乳剂栓塞治疗子宫腺肌病并不影响患者的卵巢功能,且有利于降低患者的PRL水平。
Objective To evaluate the influence on ovarian function of patients with adenomyosis after uterine artery embolization with Pingyangmycin lipiodol emulsion （PLE）. Methods Thirty-three patients with adenomyosis undergoing uterine artery embolization（UAE）with PLE whose blood been drawn to measure the level of follicle-stimulating hormone（ FSH）, luteinizing hormone（ LH）, estradiol（E2） and prolactin （PRL） before and after UAE of 1,3,6 and 12 months. Simultaneously, these sexual hormones were measured in 45 normal women serving as a normal controlled group. And then the comparison of these serum levels of sexual hormones was also carried out before and after UAE between and within both groups. Results Before this treatment no significant difference was found in the levels of FSH, LH and E2 between the treatment group（33 patients） and the controlled group, but the level of PRL in former was higher than that of the latter. In treatment group there was also no significant difference in the level of FSH, LH and E2 between the pre-UAE and post-UAE, however, the level of PRL was markedly declined at 1,3,6 and 12 months after UAE. Conclusions Transcatheter uterine artery embolization with PLE would not affect ovarian function of patients with adenomyosis, but may be helpful to decrease the level of PRL in these patients.
出处
《介入放射学杂志》
CSCD
2006年第1期14-16,共3页
Journal of Interventional Radiology
基金
广东省医学科研基金项目(B2002044)
关键词
子宫腺肌病
动脉栓塞术
子宫动脉
卵巢功能
Adenomyosis
Arterial embolization
Uterine artery
Ovarian function
