摘要
目的探讨308nm准分子激光治疗稳定期白癜风的疗效及不良反应。方法以自身未治疗皮损作为对照,采用Xtrac颠峰准分子激光系统对75例白癜风患者不同部位的皮损进行为期6周的治疗观察,每周2次,共12次,最后1次治疗结束后3d进行疗效评价并对其相关因素进行分析。结果治疗的皮损6例痊愈,33例显效,30例好转,6例无效,显效率为52.0%,有效率为92.0%;未治疗的皮损均未出现明显变化。治疗反应的影响因素分析,面颈部优于躯干四肢,躯干四肢优于肢端关节处。结论308nm准分子激光治疗稳定期白癜风疗效高、不良反应少,其疗效与皮损解剖部位相关。
Objective To determine the efficacy and safety of the 308nm excimer laser in the treatment of vitiligo. Methods A Self-controlled study was conducted. The vitiligo lesions in stable stage of 75 patients were treated twice a week by the 308 nm excimer laser for 6 weeks. The efficacy and factors related to efficacy were evaluated 3 days later after the final treatment. Results No improvement was observed in any of the untreated vitiligo lesions. However, of the treated lesions, 6 completely disappeared, 33 obtained significant improvement, 30 moderate improvement, 6 no improvement. The effective rate was 92.0% and the markedly effective rate was 52.0%. The lesions on the face and neck had a better response to the treatment than those on the trunk or limbs, and the latter responded better than those on the joints of extremities. Conclusion The 308 nm excimer laser is safe and effective in treatment of vitiligo in stable stage and the efficacy is related to the anatomic sites.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2006年第1期35-37,共3页
Chinese Journal of Dermatology
