摘要
目的 对椒目（Zanthoxylum bungeanum Maxim．）质量分数为95％的乙醇提取物的化学成分进行研究。方法 椒目用质量分数为95％的乙醇溶液回流提取，减压回收溶剂后，得浸肯加适量水混悬，依次用石油醚、氯仿、乙酸乙酯、正丁醇萃取，回收溶剂。所得各部分浸膏综合利用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、薄层色谱、重结晶等各种方法进行分离纯化，根据化合物的理化性质和波谱数据分析进行结构鉴定。结果 从椒目的乙酸乙酯萃取物中分离得到4个化合物，分别鉴定为；表儿茶素（Ⅰ）、槲皮素（Ⅱ）、24-烯-环阿尔廷酮（Ⅲ）、辛二酸（Ⅳ）。结论 化合物Ⅰ～Ⅳ均为首次从该属植物中分离得到。
Objective To study the chemical constituents of the 95 % ethanol extract from the seeds of Zanthoxylum bungeanum Maxim. Methods The seeds of Zanthoxylurn bungeanum Maxim. were extracted by 95 % EtOH under reflux. The EtOH was evaporated to dryness under reduced pressure. Then the residue was dissolved in water and extracted successively with petroleum ether, chloroform, EtOAc and n-BuOH. The EtOAc extract was further purified by silica gel, Sephadex LH-20 column and recrystallization. The structures of compounds were identified by physico-chemical characters and spectroscopic analysis. Results Four compounds are isolated from the EtOAc extract and identified as： epicatechin（ Ⅰ ）, quercetine（ Ⅱ ）, 9, 19-cyclolanost-24-en-3-one（ Ⅲ ）, octanedioic acid（ Ⅳ ）. Conclusions These four compounds are isolated from this genus for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2006年第2期91-92,108,共3页
Journal of Shenyang Pharmaceutical University
关键词
椒目
芸香科
黄酮
三萜
Zanthoxylum bungeanum Maxim.
Rutaeeae
flavonoids
triterpenoids
