摘要
目的比较血清肌酸激酶同工酶(CK-MB)质量和活性在缺血性心脏疾病中的差异和应用。方法采用免疫化学发光法和免疫抑制法同步检测血清中CK-MB的质量和活性。结果在48例缺血性心脏疾病患者中发生急性心肌梗死(AMI)12例,其CK-MB质量的诊断灵敏度和特异性分别为91.7%和65%,重度升高者9例;CK-MB活性的灵敏度和特异性分别为83.3%和62.5%,重度升高4例;肺部感染引发心脏缺血患者18例,其CK-MB质量的灵敏度和特异性分别为61.1%和58.8%,CK-MB活性则分别为33.3%和50%,质量和活性升高的程度多数为轻度升高;一般心肌缺血患者18例,二者无论从阳性率、升高倍数和在血液中出现的时间及维持时间均无明显差异。结论CK-MB质量检测优于CK-MB活性检测,特别是对AMI患者和伴有较明显感染的心肌缺血患者。
Objective To compare the difference and evaluation between the activation and quality of CK-MB in the is- chemic heart disease. Methods Immunosuppress and ICMA were used to perform the activation and quality of CK-MB together. Results 12 of 48 patients showed elevated AMI. The sensitivity and specifically is 91. 796 and 65% in the quality of CK-MB respectively. Extremely patients are 9. The sensitivity and specifically is 83.3 % and 62.5 % in the activation of CK-MB respectively. Extremely patients are 4. 18 patients were infected from the lung, and the sensitivity and specifically is 61. 1% and 58.8% in the quality of CK-MB respectively, the sensitivity and specifically is 33.3% and 50% in the activation of CK-MB respectively. Most of the quality and activation is elevated little. Other ischemie heart muscle patients were 18. There is no obvious difference between sensitivity, high level and the time of emergence, remain time in the serum. Conclusion The quality of CK-MB is prefer to the activation in the performance, Especially to AMI and the patient infected obviously.
出处
《中国心血管杂志》
2006年第1期46-47,49,共3页
Chinese Journal of Cardiovascular Medicine
