摘要
目的探讨呼吸衰竭病人的感染及抗感染治疗,为经验性抗生素应用提供参考。方法回顾性分析1999￣2000年该院收治的因肺部疾病导致呼吸衰竭的病人,观察病人的血常规、胸片、痰培养结果及抗生素应用情况,比较病人的平均住院日。结果感染诱发的呼吸衰竭不一定有胸片、血常规的变化,白细胞的高低对经验性使用抗生素的帮助有限。病原菌多见革兰氏阴性杆菌,耐药菌多。入院首选联合使用抗生素者虽呼吸衰竭重于单用者,但平均住院日无延长。结论呼吸衰竭病人抗生素的经验性不仅有赖于临床表现,还要关注本地区的细菌流行和耐药情况。有效的初始治疗、及时根据药敏试验更换抗生素有利于缩短平均住院日。
[Objective] To provide some data on the empirical antibiotic therapy in the patients of respiratory failure. [Methods] Retrospective analyzed the patients of respiratory failure induced by lung diseases. The results of chest X ray, white blood cell count, and bacterial culture were collected. The antibiotic therapy course was documented. The average in-hospital days was compared. [ Results] The infection in the patients with respiratory failure did not always accompanied by the change of chest-X ray and white blood cell count. The number of white blood cell count provided limited information on the selection of empirical antibiotics. The patients with respiratory failure might take advantage in the combination usage of antibiotics on admission. [Conclusions] It is important to pay attention to the local condition of prevalence and resistance of bacteria. Effective antibiotic therapy on admission and changing antibiotics base on the results of cultures on time can shorten the average in-hospital time.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第3期404-406,共3页
China Journal of Modern Medicine
关键词
呼吸衰竭
感染
药物治疗
respiratory insufficiency
infection
drug the,＇apy
