摘要
目前,糖尿病患病率呈现上升趋势,它已成为严重危害人类健康的疾病之一。胰岛细胞移植可以用来治疗1型和部分2型糖尿病,但由于供体细胞来源匮乏,寻找新的细胞来源成了当务之急。近年来,随着细胞移植和组织工程的日益发展,干细胞研究为新型胰岛的来源开辟了新的途径。本文综述了近年来干细胞分化为胰岛样细胞的研究进展、存在问题和可能的解决途径。
The morbidity rate of diabetes mellitus is increasing at present, which is a serious disease damaging human being＇ s health. The transplantation of pancreatic islet cells has been used to treat the diabetes type 1 and 2. However, it is necessary to search new sources of insulin-secreting cells for cell therapy of diabetes mellitus due to lacking of sufficient donor cells. With the development of cell therapy and tissue engineering in recent years, the new way of new islet cells from stem cells has be found, which can provide new islets for curing of diabetes. The progress of differentiation from stem cells into islet-like cells, problems and prospect will be discussed in the review.
出处
《生命科学》
CSCD
2006年第1期75-79,共5页
Chinese Bulletin of Life Sciences
基金
国务院侨办重点学科基金资助(2005)
关键词
干细胞
糖尿病
细胞治疗
stem cell
diabetes mellitus
cell therapy
