摘要
用ＩＲＭＡ法检测４２例乳腺癌患者术前和术后第２周血清ＣＡ１５－３值，并结合临床病理资料进行分析。结果，血清ＣＡ１５－３水平与淋巴结转移状态显著相关（Ｐ＜０．０１）；术前术后ＣＡ１５－３水平差异有显著性（Ｐ＜０．０５）；其中３例有远处转移的病人，其ＣＡ１５－３值均高于１００ｕ／ｍｌ。因而认为，血清ＣＡ１５－３水平可作为乳腺癌转移的辅助性诊断手段，并用于估计肿瘤转移的潜在可能性。
An immunoradiomeric assay (IRMA) has been used to determine circulating levels of CA 15-3 of 42 patients with breast cancer.The results indicated that the levels of CA 15-3 show a significant correlation with status of lymphatic matastases, that preoperative levels of CA 15-3 differ significantly from postoperative levels of CA 15-3 (P<0.01),and that 3 patients with distant matastases all have levels of CA 15-3 more than 100 u/ml.So it is considered that CA 15-3 might be a useful indicator in monitoring the clinical course of patients with breast cancer and be used as an adjunctive measure for diagnosis of metastatic breast cancer.
出处
《南通医学院学报》
1996年第3期333-334,共2页
ACTA Academiae Medicinae Nantong
