摘要
为了解血清ＰＬＡ２对急性胰腺炎的临床价值，应用单克隆抗体，免疫组化方法，检测２０例急性胰腺炎和１５例其他腹痛病人的血清ＰＬＡ２值。结果发现，所有急性胰腺炎病人（包括出血坏死型和水肿型），在入院当天血清ＰＬＡ２值均有明显升高，表现为阳性或强阳性，敏感性１００％，持续时间３～９天或更长；且在一定范围内随病情变化而变化，可以反应胰腺的损害程度，对胰腺炎的预后判断有一定帮助。其他腹痛病人（胆囊炎、腹膜炎、阑尾炎），ＰＬＡ２值也有不同程度升高，甚至表现为强阳性。研究表明，ＰＬＡ２对急性胰腺炎不具有特异性。
PLA 2 was measured by monoclonal antibody Immunohistochemistry assay in the serum of 20 patients with acute pancreatitis and 15 patients with other abdominal pain.We discovered that PLA 2 value in the serum of all patients with acute pancreatitis , including severe necrotizing form and mild edematousform, was significant elevation on the first day after hospital admission, showing positive or stronger positive . The clinical sensitivity was 100%; Last 3-9 days, even longer. Within the certain scope, PLA 2 value changes according to the change of disease , may reflect the extent of pancreatic tissue destruction and provide help to prognosis of pancreatitis . PLA 2 value of patients with other abdominal pain , such as:cholecystitis, peritonitis and appendicitis, also increase, and even show stronger positve. PLA 2 isn't specific to pancreatitis. It is only an important reference marker.
出处
《南通医学院学报》
1996年第3期326-328,共3页
ACTA Academiae Medicinae Nantong
关键词
急性
胰腺炎
PLA2
单克隆抗体
免疫组织化学
Acute Pancreatitis
PLA 2
Anti-PLA 2 monoclonal antibody
immunohistochemistry
