摘要
目的探讨生长抑素对肝切除术后门静脉压力的影响。方法32只家兔随机分成正常对照组、生理盐水组、生长抑素组,并建立门静脉置管及肝切除动物模型。术中及术后持续给药,比较各组间门静脉压力的差值。结果与生理盐水组比较,生长抑素组肝切除术前与术后门静脉压力的差值显著减少(P=0.003)。结论生长抑素可明显降低肝切除术后升高的门静脉压力,而且其降压作用是持续而稳定的。
Objective To study the effect of somatostatin on portal venous pressure after hepatectomy. Methods 32 rabbits were randomly divided into three groups：control group, NS group and somatostatin（SST） group. The rabbits were treated with normal saline and SST respectively after hepatectomy and the variation of portal venous pressure was compared between 3 groups. Results Comparing with normal saline group, the difference of portal venous pressure was obviously reduced in the SST group before and after hepatectomy （P〈0.05）. Conclusion Continuous instillation of somatostatin can obviously decrease the elevated portal venous pressure after hepatectomy. And it＇s decompresive effect is continuous and stable.
出处
《岭南现代临床外科》
2005年第4期302-303,共2页
Lingnan Modern Clinics in Surgery
关键词
肝切除
生长抑素
门静脉压力
Hepatic resection
Somatostatin
Portal venous pressure
