摘要
心脏血流动力学研究表明,用4.48％的刺五加按4.5ml/kg静脉推注时,对猫心肌收缩性的影响甚小,其主要作用为降低外周阻力,明显增加心排血量和冠脉流量,提高心脏指数,但不增加心肌耗氧量。刺五加可降低离体蛙心的收缩振幅,明显增加离体豚鼠心脏灌流时的冠脉流量和轻度减慢心率。静注刺五加抗哇巴因中毒时发生的室性心律失常优于苯妥英钠。
The study on cardiac hemodynamics of 4.48％AS with iv. doses of 4.5ml/kg body weight showed that the main effects were the decrease of TPVR, the remarkable increase of SV and coronary flow and the elevation of CI, but it had little effect on cardiac contractivity. The increased consumption of oxygen by cardiac muscle was not observed. AS could lower the contractive amplitude of the isolated frog's heart, however, not obviously the coronary flow of the isolated quinea pig's heart. The antagonistic action of AS on ventricular cardiac arrhymia resulting from intoxication of ouabain was superior to Dilantin.
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
1989年第4期21-25,共5页
Journal of Jinan University(Natural Science & Medicine Edition)
关键词
刺五加
心功能
血液动力学
哇巴因
Acanthopanccis Senticosi, Hemodynamic, Ouabain, Cardiac function
