摘要
目的:探讨高血压病患者血清尿酸水平与冠状动脉病变程度的相关性。方法:将经过冠状动脉造影的 368例高血压病患者分为冠心病组(n=240)和对照组(n=128),测定血清尿酸水平及其他临床生化指标,并进行对照分析。结果:冠心病组的血清尿酸为(448．32±11 5．12)μmol／L,对照组为(371．36±98．98)μmol／L,差异有统计学意义(P<0．001);多因素逐步回归分析显示高血压病患者的冠状动脉狭窄程度与血清尿酸水平呈显著线性同归关系(P<0．001)。结论:高血压病患者的血清尿酸水平与冠状动脉狭窄程度密切相关。
Objective： To investigate the correlation between serum uric acid level and coronary artery lesions of essential hypertension patients. Methods： The serum uric acid and other clinical biochemical parameters were measured in 367 essential hypertension patients who had undergone coronary angiography. According to the result of angiography,patients were divided into coronary artery disease group （n =240） and normal coronary control group （n=128）. Data of two groups were analyzed retrospectively. Results： The level of serum uric acid was significant higher in cornoary artery disease group than that in the control group [（448.32±115.12） μmol/L vs （371.36±98.98） μmol/L, P〈0. 001]. Using stepwise regression analysis, a linear regression relationship was found between serum uric acid, LDL, blood glucose two hours after meal and severity of cornoary lesions in essential hypertension patients. Conclusion： Serum uric acid level had a strong correlation with severity of coronary lesions in essential hypertension patients.
出处
《新疆医科大学学报》
CAS
2006年第1期34-35,共2页
Journal of Xinjiang Medical University
关键词
高血压病
尿酸
冠状动脉疾病
essential hypertension ,uric acid, coronary artery disease
