摘要
流行病学调查发现，帕金森病的发病率男性多于女性，动物实验和临床试验的结果也提示，雌激素对帕金森病的发生具有一定的保护作用。本文就雌激素舆雌激素受体的特性、雌激素对黑质-纹状体系统多巴胺通路的影响、雌激素在帕金森病模型中可能的神经保护作用的研究进展作一综述。
Epidemiological investigation suggests that Parkinson disease is more prevalent in men than women. Results From animal experiments and clinical trials also indicate a possibly protective influence of estrogens in predisposition to the disease. Here we summarize the characters of estrogens and estrogen receptors, the influence of estrogens to the nigrostriatal dopamine system and the possible nerval protective effects of estrogens in models of Parkinson＇s disease.
出处
《国际中华应用心理学杂志》
2006年第1期67-69,共3页
intermational chinaese application psychology journal
