摘要
Ｃ５７ＢＬ小鼠接受２５、５０、７５、１００ｍＧｙＸ线单次全身照射后，小鼠肺转移结节数明显低于对照组，其中以７５ｍＧｙ组最低。再将荷瘤小鼠进行７５ｍＧｖＸ线照射，受照组肺转移结节数仍低于对照组。与此同时发现，经７５ｍＧｙ照射的小鼠免疫功能明显增强。上述结果提示：小剂量电离辐射对肿瘤转移有抑制作用，其可能机制是其免疫刺激效应。
After irradiation with 25,50,75 or 100 mGy X-rays,lung metastatic nodules of C57 BL/Bmice were less than that of control group,and the metastatic nodules of group with 75 mGyirradiation was the least of all.We also found that the whole-body irradiation with 75mGyxrays to tumor-bearing mice caused a decrease in the number of lung metastatic nodules. Atthe same time,and 75mGy X-rays radiation may enhance mice immune function,These re-sults suggested that low dose irradiation may suppress tumor metastasis,and its possiblemechanism may be that the low dose radiation induces immunoenhancement.
出处
《上海医学》
CAS
CSCD
北大核心
1996年第3期125-125,共1页
Shanghai Medical Journal
基金
国家自然基金
关键词
低电离辐射
肿瘤转移
免疫功能
Low ionizing radiation
Tumor metastasis
Immnue function.
