摘要
目的:探讨中青年、老年子宫内膜癌的临床特点、诊治和预后。方法:对照分析82例中青年子宫内膜癌和33例老年子宫内膜癌的临床资料。结果:中青年组和老年组的腺癌分别占74.4%和75.5%。中青年组和老年组的Ⅰ期病人分别占64.6%和69.7%,Ⅲ期和Ⅳ期分别占15.9%和15.2%。G1级在中青年组和老年组中分别占70.72%和60.6%。中青年组的无肌层浸润者(42.8%)明显高于老年组(15.6%)(P<0.01)。中青年组的≥1/2肌层浸润者(10.4%)明显低于老年组(40.6%)(P<0.01)。老年组的术后辅助化疗显著多于中青年组(P<0.05)。中青年组的5年生存率(92.79%)显著高于老年组(72.21%)(P<0.05)。结论:中青年和老年子宫内膜癌都以腺癌为主,细胞分化都以高分化为主。多数中青年病人和老年病人都能在较早期就诊。早期诊断和合理治疗能进一步改善其预后。中青年子宫内膜癌病人的预后明显好于老年人,子宫肌层浸润深度可能是影响两组预后差别的主要因素之一。
Objective To explore the clinical features,diagnosis,treatment and prognosis of endometrial carcinoma in young,middle-aged and elderly women. Methods We retrospectively analyzed the clinical data of 82 cases of endometrial carcinoma in young,middle-aged women and 33 cases of endometrial cacinoma in elderly women. Results The rates of adenocarcinoma in young,middle-aged and elderly groups were 74.4% and 75.5% ,respectively. The young,middle-aged and elderly patients with Stage Ⅰ endometrial cancer were 64.6% and 69.7% , and those with Stage Ⅲ and Ⅳ were 15.9% and 15.2% , respectively. The histological Grade 1 carcinoma of endometrium in young, middle-aged and elderly women were 70. 7% and 60.6%, respectively. The young, middle-aged women without myometrial invasion were more than the elderly women （42. 8% vs 15. 6% , P〈0.01 ）, The young, middle-aged women with myometrial invasion more than half of myometrial wall were less than the elderly women （10,4% vs 40.6% ,P 〈0.01 ）, The rate of chemical treatment after the surgery in the elderly women was more than that of the young, middle-aged women （P〈0.05 ）. The 5-year survival rate of the young, middle-aged women was obviously higher than that of the elderly women （92.79% vs 72.21% , P〈0. 05）, Conclusion Adenocarcinoma and well-differentiated cells are the main pathological characteristics of endometrial carcinoma both in the young,middle-aged and the elderly women, Most young,middleaged and el-derly patients can be diagnosed and treated in the early stage. Early diagnosis and reasonable treatment can improve the prognosis, The prognosis of the young, middle-aged patients is obviously better than that of the elderly patients,and the myometrial invasion depth may be the main difference.
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2005年第6期690-693,共4页
Journal of Central South University ：Medical Science
关键词
中青年
老年
子宫内膜癌
影响因素
预后
young, middle-aged
elderly
endometrial carcinoma
influence factor
prognosis
