摘要
目的:探讨阿托品与患者感觉统合失调的关系.方法:80例使用阿托品患者分为3组:A组30例为常规0.5～1 mg阿托品解痉组,B组30例为轻、中度有机磷农药中毒治疗组,C组20例为阿托品单次5～10mg中毒组.观察各组患者给药后步态及翻身、惊厥、言语反应、辨别方向、手臂稳定性,并记录其起止时间.结果:感觉统合失调发生率:A组0%,B组26.7%,C组100%,B组、C组与A组比较,有显著性差异(P＜0.01);感觉统合失调的起止时间:开始出现异常一般在用药后30 min左右.阿托品减量后21～27 h消失,C组用药后11～19 h消失.结论:单次小剂量阿托品对患者感觉统合没有影响.小剂量、反复或大剂量使用阿托品可引起患者的感觉统合失调.
Objective： To investigate the ralation between sensory integrative dysfunction of patients and atropine. Methods： Eighty patients were divided into three groups： relieving gastrointestinal convulsion group（A n=30） with atropine dosage; treat group （B n=30） of poisoning of lorganic phosphorus pesticide;and atropine poisoning group（C n= 20） of 5- 10 mg atropine dosage singlely causing toxication. The pace form or rummage of the body, convulsions, the reaction of speak, the distinguish of direction, the steady of hand and arm were obseverd. The abnormal patients were defined into sensory integrative dysfunction in five aspects above and the time of beganging and end were recorded. Results：The incidence of sensory integrative dysfunction was 0 % in group A, 26.7% in group B and 100% in group C. There was a notably different between both group B and C and group A. The state occured in 30 minites after atropine was used and vanishsed in 21- 27 hours after the dose of atropine was reduced. But the abnormal state was vanished in group C in 11-19 hours after the dose reduced. Conclusion：Small dosage of atropine used singlely do not influence sensory integrative dysfunction, however small dosage of atropine used multifoldly or large dosage atropine may lead to sensory integrative dysfunction.
出处
《实用临床医学（江西）》
CAS
2005年第12期47-48,50,共3页
Practical Clinical Medicine
关键词
阿托品
感觉统合失调
惊厥
atropine
sensory integrative dysfunction
convulsions
