摘要
目的观察益钙宁(依降钙素)以及益钙宁和多瑞吉合用治疗骨质疏松急性爆发性骨痛的镇痛效果。方法57例老年骨质疏松爆发性骨痛患者,年龄58~92岁,平均为67.4岁,疼痛强度VAS评分为9.0±0.4,疼痛持续时间为3~8天。A组采用益钙宁20U肌肉注射,2次/W;B组益钙宁20U肌注,2次/W+多瑞吉1.25mg^2.5mg/72h。每3天评估VAS评分及临床症状、体征一次。结果两组治疗前后VAS相比均有明显差异(P<0.01),且B组出现镇痛效果早于A组。结论对急性爆发性骨痛益钙宁、辅以小剂量多瑞吉能更快速缓解疼痛。
Objective： To observe the analgesic effect of eleitonin and eleitonin plus durogesie on urgent bone pain due to osteoporosis. Methods： 57 patients aged 58 -92 years （averaged 67.4 years） were employed in this study. The VAS was 9.0 ±0. 4, and pain duration was 3 - 8 days. Group A ： eleitonin 20U i. m. , twice per week. Group B ： A ＋ durogesie （ 1.25 - 2.5mg/72h）. VAS and physical functions were assessed every 3 days. Results： There was significant difference in the therapeutic effect between preand post-treatment for both groups （P 〈 0.01 ）. Eleitonin plus durogesie produced pain relief earlier than eleitonin alone. Conclusion： Eleitonin combined with durogesie can effectively and quickly relieve urgent bone pain related to osteoporosis.
出处
《中国疼痛医学杂志》
CAS
CSCD
北大核心
2005年第6期334-336,共3页
Chinese Journal of Pain Medicine
