摘要
目的:探讨皮质醇在急性脑出血疾病中的变化。方法:采用放射免疫分析,对68例急性脑出血患者和40例正常人的血浆中皮质醇含量进行测定。结果:患者血浆中皮质醇含量较对照组明显增高(P<0.001)。皮质醇昼夜分泌规律出现明显紊乱,且上述变化与病情的严重程度呈正相关。随着病情改善,血浆皮质醇亦逐渐恢复。结论:急性脑出血患者血浆皮质醇的含量与疾病的严重程度和预后有着密切的关系。
Objective To explore the changes of plasma cortisol levels in patients with acute cerebral hemorrhage. Methods Plasma cortisol levels were measured with RIA at 24 ： 00 and 8 ： 00 right after admission in 68 patients with acute cerebral hemorrhage and the tests were repeated in 61 patients one week later 40 controls entered this study. Results The plasma cortisol levels were significantly higher in the patients than the corresponding readings in controls （P 〈0.001 ） with obliteration of the normal diurnal rhythm of secretion. The increase of the cortisol levels was positively correlated with the severity of the disease. As the condition of the patients improved, the cortisol levels dropped gradually. Conclusion The plasma cortisol levels in patients with acute cerebral hemorrhage were closely related to the severity of the disease and were of prognostic value.
出处
《放射免疫学杂志》
CAS
2005年第6期439-440,共2页
Journal of Radioimmanology
关键词
脑出血
急性期
皮质醇
血浆
含量
cerebral hemorrhage, acute stage, cortisol, plasma
