摘要
目的:研究微小肝癌的CT、超声诊断特征与其病理基础。方法:实验组由12只肝脏内含直径≤10mm单一肿瘤结节的新西兰大白兔组成。应用超声仪及螺旋CT对实验兔接种区在不同时间进行监测,取出荷瘤肝脏进行病理学检查。结果:超声检查:2只病灶中央发现血流信号,12只病灶的非中心区发现丰富血流信号。CT检查:平扫12只病灶中8只为低密度,4只为等密度。增强扫描:动脉期12只病灶都明显强化,肿瘤中央部强化不均匀。门脉期病灶非中心部强化减退,病灶中央部强化减退更明显。肝实质期,病灶强化消退,呈低密度病灶。结论:超声、CT可发现微小肝癌的异常表现,表现形式取决于肿瘤内部的组织成分、细胞排列方式。增强特点和血流动力学改变取决于肿瘤中心及周边的血管数目。
Objective： To study the relationship between US, CT features and the pathological base of micro-hepatocellular carcinoma（MHCC）. Materials and Methods： Experimental group： 12 rabbit models hearing VX2 liver tumor with the diameter≤10mm. US and spiral CT scanning were performed after implantation of VX2 tumor at different time. The liver with tumor were obtained after US and CT monitoring. HE stain was done for pathology. Statistics of t test and χ^2 were analyzed. Results： US scan： CDFI showed that the 12 tumors were hypervascular in para-center and only two tumors were found blood flowing in the center. CT scan： plain scan showed that 8 lesions were hypodense and 4 were isodense. Twelve lesions appeared markedly enhanced during hepatic arterial phase, especially at para-center hut heterogeneity enhanced in center. Enhanced density reduced gradually especially in the center of lesion in portal venous-phase. The lesion became hypodense compared with the normal parenchyma in delayed phase. Conclusion： MHCC can he detectible by follow-up US and CT. The features were depended on inside tissue-component. The change of blood kinetics and enhanced patterns had relationship with the number of small blood vessels and its vessel wall integrity.
出处
《中国临床医学影像杂志》
CAS
北大核心
2005年第12期678-681,共4页
Journal of China Clinic Medical Imaging
