摘要
目的:介绍生物医学纤维的种类及甲壳素纤维、骨胶原纤维、聚乳酸纤维等主要生物医学纤维的制备技术、性能和用途,并建议国内应重视生物医学纤维的研究与开发。资料来源:应用计算机检索http://www.sciencedirect.com,http://world-scinet.lib.tsinghua.edu.cn1993-01/2001-12的文章,检索词为“biomedi-cal,polymer,fibre”,限定文章语言种类为English;同时检索http://www.wanfangdata.com.cn1999-01/2004-12的文章,检索词为“生物,医学,高分子”,限定文章语言种类为中文。资料选择:纳入标准:与下列内容相关的文献:①甲壳素类纤维。②胶原纤维聚乳酸纤维。③海藻酸纤维。④聚乙交酯纤维。⑤β-羟基丁酸酯。⑥聚已内酯纤维。排出标准:①较陈旧的文献。②重复研究。资料提炼:共收集到60多篇与生物医用纤维有关的文献,其中15篇符合纳入标准,排出的45篇文章系同一类重复性研究和较陈旧的文献。资料综合:①生物医学纤维的种类:按来源,生物医学纤维材料包括金属生物医学纤维、无机非金属生物医学纤维和高分子生物医学纤维。按材料与活体组织的相互作用,生物医学纤维材料包括生物惰性纤维、生物活性纤维和生物吸收纤维。按生物医学用途,生物医学纤维材料包括硬组织相容性生物医学纤维、软组织相容性生物医学纤维、血液相容性生物医学纤维和药物控释生物医学纤维。②主要生物可降解纤维材料:包括甲壳素类纤维、胶原纤维、聚乳酸及其共聚物纤维等。结论:生物医学纤维作为一类重要的功能纤维已引起国内外广泛关注,其研究和开发正方兴未艾,并显示了良好的应用前景。应更加重视对生物医学纤维的研究和开发。
OBJECTIVE： To introduce the sorts of biomedical fibers, collagenous fibers, chitin fibers polyactic acid（PLA） fibers, etc. , and their preparation, properties and application respectively, and suggest China to pay attention to the research and development of biomedical fiber.
DATA SOURCES： Literatures from January 1993 to December 2001 were computer-searched in http：//www.seieneedireet.eom, http：//worldseinet.lib. tsinghua.edu.cn, with the key words of “biomedical and polymer,fibre” and the language was limited to English.： Literatures from January 1999 to December 2004 were computer-searcbed in http：//www.wanfangdata.com.cn, with the key words of “Biological, medical, polymer and Chitin Fibers” and the language was limited to Chinese.
STUDY SELECTION： Inclusion criteria： ①Chitin fibers②Collagenous fibers and PLA fibers③Alginic acid fibers④Polyglycolide fibers⑤β-hydrexybutanoic acid ester （PHB）⑥Polycaprelactone fiber. Exclusion criteria： ① Obsolete literatures. ② Repeated study.
DATA EXTRACTION： Totally 60 tests on biomedical fiber were collected, but only 15 literatures met the inclusion criteria. Altogether 45 literatures were excluded due to older and repeated study.
DATA SYNTHESIS： ①The sorts of biomedical fibers： Classified according to the sources, biomedical fibers include metal ones （e.g. stainless steel wire）, inorganic and nonmetal ones （e.g. alumina fibers） and macremolecular ones. Classified according to the interaction between living tissues and materials, they include bioinert fibers, bioactive fibers and bioabsobable fibers. Classified according to biomedical use, they include biomedical fibers compatible with hard tissues, biomedical fibers compatible with parenehyma, biomedical fibers compatible with blood and biomedical fibers used as medicine or for regulating the release of medicine ② The main biodegradable fibers include chitin fibers, collagenous fibers, PLA fibers and their copolymer fibers. CONCLUSION： As one of
出处
《中国临床康复》
CSCD
北大核心
2005年第46期181-184,共4页
Chinese Journal of Clinical Rehabilitation
