摘要
目的探讨绞股蓝冲泡灌胃给药对实验性高脂血症及血液流变学的影响,方法在给新西兰健康兔喂饲高脂饲料的同时,泡服绞股蓝微粉。结果绞股蓝微粉泡服具有显著地降脂、降黏、改善血液流变性、红细胞变形性和微循环等作用。结论表明绞股蓝微粉泡服是一种既能降脂又能改善血液流变学的药物。
OBJECTIVE To observe the effects of Gynostemma pentaphyUum on the blood-lipid and hemorheology in hyperlipidemia rabbits. METHODS Total cholesterol （ TC）, triglyceride （ TG）, low density lipoprotein （ LDL）, high density lipoprotein, parameters of hemorheology in serum were determined after the hyperlipidemia rabbits were established and administrated with Gynostemma pentaphyUum. RESULTS Hyperlipidemia rabbits＇ models were established by feeding hyperlipi-diet. The TC ,TG LDL, HDL were decreased remarkably,the parameters of hemorheology, whole blood viscosity, plasma viscosity, RBC accumulation and RBC deformation were reduced obviously by Gynostemma pentaphyUum. CONCLUSION The results show that Gynostemma pentaphyUum can obviously decrease the blood-lipid and improve hemorheology in hyperlipidemia rabbits.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2005年第6期454-455,共2页
Chinese Journal of Modern Applied Pharmacy
关键词
绞股蓝
高脂血症
血液流变学
Gynostemma pentaphyllum
hyperlipidemia
hemorheology
