摘要
目的观察上海地区黄胸鼠和褐家鼠对第一代和第二代抗凝血灭鼠剂的抗药性,分析原因,制定对策。方法现场捕获褐家鼠和黄胸鼠,按照全国鼠类抗药性监测协作组统一的方法进行无选择性摄毒试验,分别摄食0.005%、0.05%杀鼠灵毒饵和0.005%溴敌隆毒饵。结果对杀鼠灵抗药性,44只褐家鼠中发生率为2.27%,29只黄胸鼠中发生率为13.79%;对溴敌隆抗药性,42只褐家鼠中发生率为4.76%,10只黄胸鼠中发生率10.00%;对杀鼠灵和溴敌隆毒饵产生抗药性的黄胸鼠个体分别对溴敌隆和杀鼠灵毒饵产生交互抗性。结论(1)当停用第一代抗凝血灭鼠剂14年后,褐家鼠对杀鼠灵的抗性发生率有明显的衰退现象,黄胸鼠对杀鼠灵的抗性水平未发生明显变化;(2)在连续15年使用溴敌隆后,上海地区的褐家鼠和黄胸鼠均对溴敌隆产生了抗性个体;(3)建议尽快建立鼠类对第二代抗凝血灭鼠剂抗药性检验方法、抗药性个体和种群的判断标准。
Objective To study the rodenticides resistance, where first and second anticoagulant rodenticide were used in two commensal rodents control in Shanghai. Methods The in-taking toxicity was tested by unselective method in Rattus flavipectus and R. norvegicus at both 0.05 % warfarin bait and 0.005 % bromadiolone bait. Results R. ,flavipectus and R. norvegicus caught in four districts of Shanghai were tested, the resistance individual rate of R. norvegicus to warfarin is 2.27% , R. flavipectus 13.79% , the resistance rate of R. norvegicus to bromadiolone is 4.76 % and R..flavipectus 10.00%. Cross resistance was found in R, flavipectus. Conclusion After 14 years un-using warfarin, the resistance rate of R. norvegicus to warfarin decreased, but R. flavipectus had no changes. After using bromadiolone for 15 years, the resistance rate of R. norvegicus and R. flavipectus to bromadiolone had developed.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
北大核心
2005年第6期427-429,共3页
Chinese Journal of Vector Biology and Control
关键词
家栖鼠
抗凝血灭鼠剂
杀鼠灵
溴敌隆
抗药性
Commensal rodent
Anticoagulant rodenticide
Warfarin
Bromadiolone
Resistance
