摘要
应用重组人αlb 型干扰素,对感染人乳头瘤病毒16型(HPV-16)和人巨细胞病毒(HCMV)的孕妇进行宫颈贴敷治疗,结果表明:疗前孕妇 HPV-16和 HCMV 的感染率分别为70.6%和41.0%,经干扰素治疗后,HPV-16和 HCMV 的感染阳性率分别下降到41.0%和23.5%。所有标本均采用聚合酶链反应技术(PCR)进行检测,证明重组人αlb 型干扰素对 HPV-16和 HCMV 有明显的抑制作用,可用于孕妇产道病毒感染的治疗。
In the present study the pregnant women infected with HPV-16 and HCMV were treated with rhIFN- α1b.The samples from genital tract before and after treatment were detected by PCR.The results obtained were as follows:the positive infection rates of HPV-16 and HCMV in pregnant women were 70.6% and 41.0% respectively, after treatment with rhIFN-α1b,the positive infection rates reduced to 41.0% and 23.5% respectively.It appears that rhIFN-α1b has inhibitive activity to the viruses and it may be used as treatment to the pregnant women with HPV- 16 and HCMV infection.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1996年第2期122-123,共2页
Chinese Journal of Experimental and Clinical Virology
