摘要
目的:探讨留置螺旋形鼻空肠管行早期肠内营养在危重病人中的应用价值。方法:对该院ICU收治的30例危重病人随机分为A组和B组,每组各15例。分别留置螺旋形鼻空肠管和鼻胃管进行早期肠内营养。入科后第1天和第8天分别测定血液T淋巴细胞亚群变化,并进行比较。结果:入科后第1天,A、B组间CD3+、CD4+和CD4+/CD8+,差异无显著性意义(P>0.05);第8天A组CD3+、CD4+和CD4+/CD8+比第1天均显著增加(P<0.05),惟CD8+无显著差异(P>0.05);而B组上述指标无明显变化(P>0.05)。当天两组间CD3+、CD4+和CD4+/CD8+也存在显著差异(P<0.05),惟CD8+无显著差异(P>0.05)。而且A组胃内潴留、急性胃黏膜病变等并发症显著减少(P<0.05);A组在ICU时间较B组缩短(P<0.05)。结论:危重病人留置鼻空肠管行早期肠内营养对细胞免疫有积极影响,能减少并发症的发生,并能缩短入住ICU的时间。
Objective： To explore the application of early enteral nutrition in critically ill patients. Methods： The 30 patients in our ICU were randomly divided into A or B group supported with early enteral nutrition through naso-jejunal tube or naso-gastric tube. Lymphocyte subsets were determined on the 1st, 8th . The date were analyzed statistically. Results： Compared to B group, CD3^＋, CD4^＋, CD4^＋ / CD8^＋ in A group on the 1 st day were not different significantly （ P 〉 0.05 ）. CD3^＋ , CD4^＋, CD4^＋/ CD8^＋ in A group on the 8th day were higher （P 〈0.05） than those on the 1st day. CD3^＋, CD4^＋ , CD4^＋/ CD8^＋ in B group on the 8th day were not higher（P 〉0.05） than those on the 1st day. Compared to B group, CD3^＋ , CD4^＋, CD4^＋/ CD8^＋ in A group on the 8th day were increased significantly（P 〈 0.05）. Compared to B group, ICU stay time was shorten significantly（ P 〈 0.05） in A group. Conclusion： Early enteral nutrition by naso-jejunal tube could not only improve cell immune function, but also reduce ICU stay time in critical ill patients.
出处
《肠外与肠内营养》
CAS
2005年第6期332-334,共3页
Parenteral & Enteral Nutrition
基金
温州市科委发展计划项目(批准号:S2002A180)
关键词
早期肠内营养
危重病
细胞免疫
并发症
Early enteral nutrition
Critical illness
Cell immune
Complications
