摘要
目的研究不同哺乳阶段母乳中淀粉酶活性变化和婴儿自身胰淀粉酶的发育规律.方法观察37例足月顺产产妇不同泌乳期和一次喂奶前、中、后段母乳中淀粉酶活性的变化;测定92例新生儿和132例1岁以内婴儿血清胰淀粉酶活性.结果初乳中淀粉酶活性较高,为(9772.37±1.70)IU/L,随着泌乳期的延长,淀粉酶活性逐渐下降.3个月后各阶段成熟乳中淀粉酶活性基本处于一个平台期(P＞0.05).一次喂奶前、中、后段,母乳中淀粉酶活性较恒定,但不同产妇间淀粉酶活性存在较大的差异.母乳淀粉酶98%为唾液型淀粉酶.新生儿期血清胰淀粉酶活性最低,随着年龄增长,胰淀粉酶活性逐渐增高,但整个婴儿期胰淀粉酶活性仅为成人的15%～30%.结论母乳中含有丰富的淀粉酶,对母乳喂养儿的淀粉消化和潜在的抗感染作用具有重要意义,应提倡母乳喂养.
Objective To explore the dynamic changes of amylase in the milk of the lactating mothers and the development of pancreatic amylase of infants. Methods The amylase activities in the milk from 37 mothers of full term infants were determined at different periods of lactation and also at the initial, middle and late periods of nursing. We also measured serum pancreatic amylase activity in 92 newborn infants and 132 infants less than one year. Results Amylase activity was higher in colostrum （9772.37 ± 1.70） IU/L, and decreased to a plateau at 3～12 months. Amylase activity didn＇t vary during feeding, but each mother had a characteristic level of activity in her milk. 98% of amylase of human milk was of the salivary type. Serum pancreatic amylase activity was very low in the newborn infants but increased with their age. Serum pancreatic amylase activity in infants was found to be 15%～30% of that in adults. Conclusion Human milk is rich in amylase. Breast-milk amylase contributes to the breastfed infant＇s ability to digest starch. It is worthy to be recommended.
出处
《上海第二医科大学学报》
CSCD
北大核心
2005年第11期1102-1104,共3页
Acta Universitatis Medicinalis Secondae Shanghai
关键词
母乳
淀粉酶
婴儿
human milk
amylase
infant
